Results 41 to 50 of about 5,876,781 (310)

Efficient Genomic Prediction of Yield and Dry Matter in Hybrid Potato

open access: yesPlants, 2023
There is an ongoing endeavor within the potato breeding sector to rapidly adapt potato from a clonal polyploid crop to a diploid hybrid potato crop.
James Adams   +2 more
doaj   +1 more source

Deep Sequencing of FLT3‐ITD Enables Response Evaluation and Post‐Treatment Monitoring in Childhood AML: An Exploratory Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm   +11 more
wiley   +1 more source

A guided network estimation approach using multi-omic information

open access: yesBMC Bioinformatics
Intoduction In systems biology, an organism is viewed as a system of interconnected molecular entities. To understand the functioning of organisms it is essential to integrate information about the variations in the concentrations of those molecular ...
Georgios Bartzis   +3 more
doaj   +1 more source

Notes on D‑optimal Spring Balance Weighing Designs

open access: yesActa Universitatis Lodziensis. Folia Oeconomica, 2018
Spring balance weighing design is a model of an experiment in which the result can be presented as a linear combination of unknown measurements of objects with factors of this combination equalling zero or one. In this paper, we assume that the variances
Bronisław Ceranka, Małgorzata Graczyk
doaj   +1 more source

Time Toxicity in Wilms Tumor: Quantifying the Burden of Healthcare Interaction in the First Year After Diagnosis

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Wilms tumor (WT) treatment imposes a significant time burden on patients and their families. Time toxicity is a patient‐centered metric that quantifies the burden of healthcare interaction. We sought to define time toxicity in the first year after diagnosis of WT and hypothesized that it would increase as tumor stage and treatment ...
Caleb Q. Ashbrook   +6 more
wiley   +1 more source

Clinical and biological risk factors influencing infant HIV status: a case study of Kisenyi Health Center IV, Kampala, Uganda

open access: yesBMC Infectious Diseases
Background Transmission of HIV from mother to child (MTCT) contributes to 18% of new HIV infections in Uganda. This study aimed at investigating how clinical and biological risk factors were associated with the transmission of HIV from mothers to ...
Francis Xavier Bagonza   +3 more
doaj   +1 more source

Heterogeneity in the Global Practice of Central Nervous System Staging in Pediatric Acute Lymphoblastic Leukemia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) involvement in childhood acute lymphoblastic leukemia (ALL) is assessed by cell counting and cytomorphology from cerebrospinal fluid (CSF) and is used for treatment stratification worldwide. The ratio of “CNS2” patients in clinical trials ranges from 3% to 40%, with unclear prognostic significance ...
Laura Almási   +14 more
wiley   +1 more source

A Highly D‑efficient Spring Balance Weighing Design for an Even Number of Objects

open access: yesActa Universitatis Lodziensis. Folia Oeconomica, 2019
The problem of determining unknown measurements of objects in the model of spring balance weighing designs is presented. These designs are considered under the assumption that experimental errors are uncorrelated and that they have the same variances ...
Małgorzata Graczyk, Bronisław Ceranka
doaj   +1 more source

Notes on Selected Optimal Weighing Designs

open access: yesActa Universitatis Lodziensis. Folia Oeconomica, 2021
In this paper, some problems related to the construction of highly D‑efficient spring balance weighing designs are presented. We give some conditions determining the relations between the parameters of such designs and construction examples.
Małgorzata Graczyk, Bronisław Ceranka
doaj   +1 more source

Emapalumab for Immune Effector Cell‐Associated Hemophagocytic Lymphohistiocytosis‐Like Syndrome Following CD19‐Directed CAR‐T in Two Patients With B‐ALL: Clinical and Biomarker Correlates

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta   +6 more
wiley   +1 more source

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