Results 31 to 40 of about 2,740,785 (266)

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács   +8 more
wiley   +1 more source

Pulmonary Dysfunction Is Associated With Sleep Study Abnormalities in Children With Sickle Cell Disease: A Multicenter Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Pulmonary dysfunction and sleep abnormalities are common in children with sickle cell disease (SCD) and are associated with worse clinical outcomes. Whether spirometry abnormalities are associated with polysomnography (PSG) findings remains unclear.
Ammar Saadoon Alishlash   +4 more
wiley   +1 more source

An Efficient Approach for Computing Optimal Low-Rank Regularized Inverse Matrices [PDF]

open access: yes, 2014
Standard regularization methods that are used to compute solutions to ill-posed inverse problems require knowledge of the forward model. In many real-life applications, the forward model is not known, but training data is readily available. In this paper,
Chung, Julianne, Chung, Matthias
core   +1 more source

Financial Burden Associated With Hospitalisation Among Families of Childhood Brain Tumours in Australia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Families of children with cancer experience significant financial strain, even with universal healthcare. Indirect costs, such as productivity losses and non‐medical expenses, are rarely included in economic evaluations, and little is known about how effectively financial aid programmes alleviate this burden. Childhood brain tumours
Megumi Lim   +8 more
wiley   +1 more source

Actuarial and various entropy measures for a new extended log Kumaraswamy model: Properties and applications

open access: yesAlexandria Engineering Journal
This article introduces a novel extension of the log Kumaraswamy distribution, termed Marshall Olkin log Kumaraswamy (MOLkw). The mathematical and statistical characteristics of the suggested distribution are constructed, encompassing explicit ...
Naif Alotaibi
doaj   +1 more source

Most ankle sprain research is either false or clinically unimportant: A 30-year audit of randomized controlled trials

open access: yesJournal of Sport and Health Science, 2021
Background: Lateral ankle sprain is the most common musculoskeletal injury. Although clinical research in this field is growing, there is a broader concern that clinical trial outcomes are often false and fail to translate into patient benefits. Methods:
Chris M. Bleakley   +2 more
doaj   +1 more source

Statistical and Numerical Study of Asteroid Orbital Uncertainty [PDF]

open access: yes, 2013
The knowledge of the orbit or the ephemeris uncertainty of asteroid presents a particular interest for various purposes. These quantities are for instance useful for recovering asteroids, for identifying lost asteroids or for planning stellar occultation
Bancelin, David   +3 more
core   +4 more sources

Inpatient Food Insecurity and Pediatric Hematology Oncology Hospitalization Outcomes

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Children with cancer and blood disorders are at risk for food insecurity (FI). We aimed to describe the association of inpatient food insecurity (IFI) and hospitalization outcomes among patients admitted to the pediatric hematology oncology service. Of 325 caregivers screened for IFI, 60 (18.6%) screened positive.
Joanna M. Robles   +4 more
wiley   +1 more source

Efficacy and Safety Analysis of Roxarestat in Regulating Renal Anemia in Patients on Maintenance Hemodialysis

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Objective To compare the efficacy and safety of roxarestat versus recombinant human erythropoietin (rhEPO) in the management of renal anemia in patients undergoing maintenance hemodialysis. Methods This was a prospective, open‐label, randomized controlled trial.
Lingling Chen, Junjie Zhu, Qiaonan Ge
wiley   +1 more source

Research on the measurement of general risk preference based on multivariate statistical analysis methods

open access: yesHighlights in Business, Economics and Management
It is of great significance to study general risk preference for different populations to take targeted interventions to reduce potentially risky behaviors. In this paper, the results of Balloon Analogue Risk Task (BART) experiment are analyzed by single factor analysis of variance.
Jiachen Guang, Xuyi Shi
openaire   +1 more source

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