Results 211 to 220 of about 33,140,363 (390)

Statistical Model Choice

, 2016
G. Claeskens
semanticscholar   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

STANCE: a unified statistical model to detect cell-type-specific spatially variable genes in spatial transcriptomics. [PDF]

Nat Commun
Su H, Wu Y, Chen B, Cui Y.
europepmc   +1 more source

eSMC: a statistical model to infer admixture events from individual genomics data. [PDF]

BMC Genomics, 2022
Wang Y, Zhao Z, Miao X, Wang Y, Qian X, Chen L, Wang C, Li S.   +7 more
europepmc   +1 more source

AD Model Builder: using automatic differentiation for statistical inference of highly parameterized complex nonlinear models

Optim. Methods Softw., 2012
D. Fournier, H. Skaug, John Ancheta, J. Ianelli, A. Magnusson, M. Maunder, Anders Nielsen, J. Sibert   +7 more
semanticscholar   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Difficult-to-treat psoriatic arthritis: refining the definition using a statistical model in a real-life cohort. [PDF]

Front Med (Lausanne)
Favalli EG, Biganzoli G, Cincinelli G, Ferrito M, Luconi E, Manara M, Biggioggero M, Boracchi P, Caporali R.   +8 more
europepmc   +1 more source

Bias-Variance Aware Integration of Judgmental Forecasts and Statistical Models

, 2016
Sebastian M. Blanc
openalex   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Relationship between Household Tuberculosis and Socioeconomic and Bioenvironmental Factors: A Statistical Model Approach Using NFHS-5 Data. [PDF]

Indian J Community Med
Pandey AK, Chaturvedi HK, Choraria P.
europepmc   +1 more source