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临床预测模型常用统计模型及其SAS实现

open access: yesZhongguo cuzhong zazhi
摘要: 临床预测模型在医学研究中的应用越来越广泛,欲达到良好的预测性能,选择正确的模型非常关键。对于预测模型类型的选择,预测结局的类型起着决定性作用。本文从数据类型的角度出发,将结局变量分为连续变量(正态分布、偏态分布)、分类变量(二分类、无序多分类、有序多分类)以及时间-事件变量(无竞争风险、有竞争风险),分别介绍不同类型结局变量的特点、对应的模型、建模案例以及SAS实现程序,以期为研究者构建预测模型提供参考。 Abstract: The application of clinical ...
杨凯璇,谷鸿秋
doaj   +1 more source

Carcinomas and Carcinoid Tumors of the Lungs and Bronchi in Children and Adolescents: The EXPeRT Recommendations

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Primary lung carcinomas and bronchial carcinoid tumors (BC) are very rare malignancies in childhood. While typical BC and mucoepidermoid carcinomas are mostly low‐grade, localized tumors with a more favorable prognosis than in adults, necessitating avoidance of overtreatment, adenocarcinomas of the lung are often diagnosed at advanced disease ...
Michael Abele   +19 more
wiley   +1 more source

Health‐Related Quality of Life and Symptom Severity Among Patients With PIK3CA‐Related Overgrowth Spectrum: A Mixed‐Methods Study to Understand Real‐World Experience With Alpelisib Treatment

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu   +8 more
wiley   +1 more source

Statistical Model Development for Estimating Soil Hydraulic Conductivity Through On-Site Investigations

open access: yesHydrology
In arid regions, irrigated agriculture is mainly dependent on groundwater. In Pakistan, 73% of agricultural land is directly or indirectly irrigated through groundwater.
Muhammad Waleed   +6 more
doaj   +1 more source

Predicting Cervical Cancer Outcomes: Statistics, Images, and Machine Learning

open access: yesFrontiers in Artificial Intelligence, 2021
Cervical cancer is a very common and severe disease in women worldwide. Accurate prediction of its clinical outcomes will help adjust or optimize the treatment of cervical cancer and benefit the patients.
Wei Luo
doaj   +1 more source

Clinical and Biological Features of Response in Resistant Neuroblastoma to 131I‐Metaiodobenzylguanidine Radiotherapy in the Anti‐GD2 Immunotherapy Era

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background 131I‐metaiodobenzylguanidine (131I‐MIBG) radiotherapy is a key treatment for relapsed and refractory (R/R) neuroblastoma (NB). Patients with R/R disease treated in the modern era are increasingly exposed to anti‐GD2 immunotherapy, which exerts selective pressure and may modify both tumor cell state and microenvironment.
Benjamin J. Lerman   +7 more
wiley   +1 more source

Hospitalization Through Families’ Eyes: Comparing Inpatient Care Quality for Children With Sickle Cell Disease and Cystic Fibrosis in Canada

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Sickle cell disease (SCD) is a chronic, inherited hemoglobinopathy that requires frequent hospitalization for disease‐related complications. Canadian data on inpatient care is limited. This study compared caregiver‐reported hospital experiences of children with SCD to those with cystic fibrosis (CF), a chronic, autosomal recessive ...
Hailey M. Zwicker   +11 more
wiley   +1 more source

Generating atmospheric forcing perturbations for an ocean data assimilation ensemble

open access: yesTellus: Series A, Dynamic Meteorology and Oceanography, 2019
Running ensemble of reanalyses or forecasts has proved successful at improving their performances, despite the cost. Generating ensemble simulations requires generating perturbations within the models, and for the assimilated observations and subsidiary ...
Isabelle Mirouze, Andrea Storto
doaj   +1 more source

Venous Thromboembolism in Pediatric Bone Sarcoma Patients: A 10‐Year, Single‐Institution Experience Encompassing the COVID‐19 Pandemic

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Osteosarcoma (OS) and Ewing sarcoma (EWS) are the most common primary bone cancers in children, but acute thrombosis is poorly characterized in this population. Our study evaluated the rates of venous thromboembolism (VTE) and associated risk factors in pediatric patients with bone sarcomas treated over a 10‐year period encompassing
Sarah Kappa   +8 more
wiley   +1 more source

Sense of Coherence, Sociodemographic, Lifestyle, and Health-related Factors in Older Adults' Subjective Well-being

open access: yesInternational Journal of Gerontology, 2015
Objectives: This research explores a structural model of predictors of subjective well-being (SWB) in a community-dwelling older population.
Sofia von Humboldt   +2 more
doaj   +1 more source

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