Results 161 to 170 of about 4,326,503 (305)

Statistical Modelling of Carbonation Process in Reinforced Concrete Structure. [PDF]

Materials (Basel), 2022
Liu Y, Lin P, He Z, Ma J.
europepmc   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Long-term projections of cancer prevalence in Australia to 2050: a population-based statistical modelling study. [PDF]

Lancet Reg Health West Pac
Luo Q, Smith DP, David M, Feletto E, Kahn C, Steinberg J, Jefford M, Canfell K.   +7 more
europepmc   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Statistical modelling of an outcome variable with integrated multi-omics. [PDF]

BMC Bioinformatics
Li H, Gu Z, El Bouhaddani S, Houwing-Duistermaat J.   +3 more
europepmc   +1 more source

Understanding the age spectrum of respiratory syncytial virus associated hospitalisation and mortality burden based on statistical modelling methods: a systematic analysis. [PDF]

BMC Med, 2023
Cong B, Dighero I, Zhang T, Chung A, Nair H, Li Y.   +5 more
europepmc   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Statistical Modelling of Waning Immunity After Shanchol™ Vaccination: A Prospective Cohort Study. [PDF]

Vaccines (Basel)
Bosomprah S, Liswaniso F, Phiri B, Chibuye M, Luchen CC, Ng'ombe H, Chibesa K, Ngosa D, Muchimba M, Debes AK, Chilengi R, Sack DA, Chisenga CC.   +12 more
europepmc   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Assessing the effectiveness of seasonal malaria chemoprevention on malaria burden among children under 5 in northern Benin: a statistical modelling approach. [PDF]

BMJ Public Health
Sonounameto RC, Damien BG, Sambo TA, Houndjo W, Aissan J, Aikpon R, Dandonougbo C, Glèlè Kakaï R, Pothin E.   +8 more
europepmc   +1 more source