Results 261 to 270 of about 30,979,719 (362)

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Sexual dimorphism of the humerus bones in a French sample: comparison of several statistical models including machine learning models. [PDF]

Int J Legal Med
Blanc M, Knecht S, Nguyen K, Poulain C, Quatrehomme G, Alunni V, Nogueira L.   +6 more
europepmc   +1 more source

Nuclear Statistical Equilibrium for compact stars: modelling the nuclear energy functional

, 2015
François Aymard
openalex   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Evaluation of Machine Learning and Traditional Statistical Models to Assess the Value of Stroke Genetic Liability for Prediction of Risk of Stroke Within the UK Biobank. [PDF]

Healthcare (Basel)
MacCarthy G, Pazoki R.
europepmc   +1 more source

Hierarchical statistical modeling of rates and variability of sea level

, 2018
Erica Ashe
openalex   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Statistical models and implant customization in hip arthroplasty: Seeking patient satisfaction through design. [PDF]

Heliyon
Quiceno E, Correa CD, Tamayo JA, Zuleta AA.   +3 more
europepmc   +1 more source

Statistical Model of the Statistical Saturation Attack

, 2015
Khan
openalex   +1 more source