The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan +6 more
wiley +1 more source
Can machine learning models improve the prediction of surgical site infection in abdominal surgery than traditional statistical models? [PDF]
Piebpien P +7 more
europepmc +1 more source
Asymptotic properties of a class of statistical models in software reliability
M.C. Pul
openalex +1 more source
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani +7 more
wiley +1 more source
Statistical Models for High-Risk Intestinal Metaplasia with DNA Methylation Profiling. [PDF]
Wang T, Huang Y, Yang J.
europepmc +1 more source
Malignancy risk stratification for pulmonary nodules: comparing a deep learning approach to multiparametric statistical models in different disease groups. [PDF]
Piskorski L +11 more
europepmc +1 more source
Supervised machine learning statistical models for visual outcome prediction in macular hole surgery: a single-surgeon, standardized surgery study. [PDF]
Godani K +7 more
europepmc +1 more source
Comparing performances of different statistical models and multiple threshold methods in a nested association mapping population of wheat. [PDF]
Sandhu KS +4 more
europepmc +1 more source
Statistical modeling of mechanical bearing life testing
Sébastien Blachère +7 more
openalex +1 more source

