Results 101 to 110 of about 5,245,882 (320)
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Química Nova, 2010 The spread of Brasília isn't accompanied by correct support of land occupation, situation that is reflected in water quality. Under the optics of land use and occupation, working with multivariate statistics as main tool, water physical and chemical ...
Luiz Henrique Amorim Moura +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Design and advancement status of the Beam Expander Testing X-ray facility (BEaTriX)
, 2016 The BEaTriX (Beam Expander Testing X-ray facility) project is an X-ray apparatus under construction at INAF/OAB to generate a broad (200 x 60 mm2), uniform and low-divergent X-ray beam within a small lab (6 x 15 m2).
Arcangeli, L. +12 more
core +1 more source
NKCC1: A key regulator of glioblastoma progression
Molecular Oncology, EarlyView.Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen +5 more
wiley +1 more source
Spatial-Temporal Self-Focusing of Partially Coherent Pulsed Beams in Dispersive Medium
Applied Sciences, 2019 Partially coherent pulsed beams have many applications in pulse shaping, fiber optics, ghost imaging, etc. In this paper, a novel class of partially coherent pulsed (PCP) sources with circular spatial coherence distribution and sinc temporal coherence ...
Zhiguo Zhao +3 more
doaj +1 more source
Transverse coherence properties of X-ray beams in third-generation synchrotron radiation sources
, 2008 This article describes a complete theory of spatial coherence for undulator radiation sources. Current estimations of coherence properties often assume that undulator sources are quasi-homogeneous, like thermal sources, and rely on the application of the
Bahrdt +23 more
core +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Correlation of Intensity Fluctuations for Scattering of a Partially Coherent Plane-Wave Pulse
Applied Sciences, 2019 We derived analytical expressions for the correlation of intensity fluctuations of a partially coherent Gaussian Schell-model plane-wave pulse scattered by deterministic and random media.
Yongtao Zhang +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source