Results 11 to 20 of about 1,502,987 (305)

A Fast Multi-Locus Ridge Regression Algorithm for High-Dimensional Genome-Wide Association Studies

open access: yesFrontiers in Genetics, 2021
The mixed linear model (MLM) has been widely used in genome-wide association study (GWAS) to dissect quantitative traits in human, animal, and plant genetics.
Jin Zhang   +7 more
doaj   +1 more source

Low statistical power in biomedical science: a review of three human research domains [PDF]

open access: yesRoyal Society Open Science, 2017
Studies with low statistical power increase the likelihood that a statistically significant finding represents a false positive result. We conducted a review of meta-analyses of studies investigating the association of biological, environmental or ...
Estelle Dumas-Mallet   +4 more
doaj   +1 more source

AGNEP: An Agglomerative Nesting Clustering Algorithm for Phenotypic Dimension Reduction in Joint Analysis of Multiple Phenotypes

open access: yesFrontiers in Genetics, 2021
Genome-wide association study (GWAS) has identified thousands of genetic variants associated with complex traits and diseases. Compared with analyzing a single phenotype at a time, the joint analysis of multiple phenotypes can improve statistical power ...
Fengrong Liu   +6 more
doaj   +1 more source

Reliability of animal counts and implications for the interpretation of trends

open access: yesEcology and Evolution, 2021
Population time series analysis is an integral part of conservation biology in the current context of global changes. To quantify changes in population size, wildlife counts only provide estimates because of various sources of error. When unaccounted for,
David Vallecillo   +6 more
doaj   +1 more source

Utilizing harmonization and common surveillance methods to consolidate 4 cohorts: the Western Alaska Tribal Collaborative for Health (WATCH) study [PDF]

open access: yesInternational Journal of Circumpolar Health, 2013
Background. According to health status reports, chronic disease prevalence appears to be rising in western Alaska Native (AN) people, and accurate population-based data are needed.
Kathryn R. Koller   +10 more
doaj   +1 more source

Correction: Why Psychologists Should by Default Use Welch’s 't'-test Instead of Student’s 't'-test

open access: yesInternational Review of Social Psychology, 2022
This article details a correction to: Delacre, M., Lakens, D., & Leys, C. (2017). Why Psychologists Should by Default Use Welch’s 't'-test Instead of Student’s t-test. 'International Review of Social Psychology', 30(1), 92–101.
Marie Delacre   +2 more
doaj   +1 more source

Partial least squares regression can aid in detecting differential abundance of multiple features in sets of metagenomic samples

open access: yesFrontiers in Genetics, 2015
It is now feasible to examine the composition and diversity of microbial communities (i.e., `microbiomes‘) that populate different human organs and orifices using DNA sequencing and related technologies.
Ondrej eLibiger   +2 more
doaj   +1 more source

Evaluation of autumn mist‐netting data for monitoring passerine populations in interior Alaska

open access: yesWildlife Society Bulletin, 2012
We evaluated the data from 2 autumn mist‐netting stations for monitoring passerine population trends and measuring the timing of migration. Migration‐monitoring stations were operated during autumn from 1993 to 2009 at 2 interior Alaska locations: in ...
Anna‐Marie Benson   +3 more
doaj   +1 more source

Design sensitivity and statistical power in acceptability judgment experiments

open access: yesGlossa, 2017
Previous investigations into the validity of acceptability judgment data have focused almost exclusively on type I errors (or false positives) because of the consequences of such errors for syntactic theories (Sprouse & Almeida 2012; Sprouse et al ...
Diogo Almeida, Jon Sprouse
doaj   +2 more sources

Admixed Populations Improve Power for Variant Discovery and Portability in Genome-Wide Association Studies

open access: yesFrontiers in Genetics, 2021
Genome-wide association studies (GWAS) are primarily conducted in single-ancestry settings. The low transferability of results has limited our understanding of human genetic architecture across a range of complex traits.
Meng Lin   +4 more
doaj   +1 more source

Home - About - Disclaimer - Privacy