Results 11 to 20 of about 14,418,222 (275)
Frontiers in Genetics, 2021 Genome-wide association study (GWAS) has identified thousands of genetic variants associated with complex traits and diseases. Compared with analyzing a single phenotype at a time, the joint analysis of multiple phenotypes can improve statistical power ...
Fengrong Liu +6 more
doaj +1 more source
The lack of statistical power of subgroup analyses in meta-analyses: a cautionary note
Epidemiology and Psychiatric Sciences, 2021 One of the most used methods to examine sources of heterogeneity in meta-analyses is the so-called ‘subgroup analysis’. In a subgroup analysis, the included studies are divided into two or more subgroups, and it is tested whether the pooled effect sizes ...
P. Cuijpers +2 more
semanticscholar +1 more source
Frontiers in Genetics, 2021 Genome-wide association studies (GWAS) are primarily conducted in single-ancestry settings. The low transferability of results has limited our understanding of human genetic architecture across a range of complex traits.
Meng Lin +4 more
doaj +1 more source
Theory and practice of clinical trials in oncology and hematology
Онкогематология, 2016 In the era of evidence-based medicine the main reason for the implementation of new treatment methods are the results of clinical trials. However, clinical trials is a separate area of knowledge, which is often little known to clinicians, that does not ...
N. V. Zhukov
doaj +1 more source
Calculating statistical power for meta-analysis using metapower
, 2021 Meta-analysis is an influential evidence synthesis technique that summarizes a body of research. Though impactful, meta-analyses fundamentally depend on the literature being sufficiently large to generate meaningful conclusions.
Jason W. Griffin
semanticscholar +1 more source
Frontiers in Psychology, 2015 In recent years, cognitive scientists and commercial interests (e.g., Fit Brains, Lumosity) have focused research attention and financial resources on cognitive tasks, especially working memory tasks, to explore and exploit possible transfer effects to ...
Tim eBogg, Leanne eLasecki
doaj +1 more source
Classical Conditioning for Pain: The Development of a Customized Single-Case Experimental Design
Journal of Trial and Error, 2022 Single-case experiments are increasingly popular in the behavioral sciences. Due to their flexibility, single-case designs can be customized to test a variety of experimental hypotheses.
Tamal Kumar De +3 more
doaj +1 more source
Using genomic annotations increases statistical power to detect eGenes. [PDF]
, 2016 MotivationExpression quantitative trait loci (eQTLs) are genetic variants that affect gene expression. In eQTL studies, one important task is to find eGenes or genes whose expressions are associated with at least one eQTL. The standard statistical method
Duong, Dat +6 more
core +1 more source
Southern African Journal of Infectious Diseases, 2016 Randomisation is an integral component of any sensible clinical trial. Randomisation is the only way we can be sure that the patients have been allocated into the treatment arms with as minimum bias as possible, and that the treatment arms are similar ...
Jesca M. Batidzirai
doaj +1 more source
Statistical Power Supply Dynamic Noise Prediction in Hierarchical Power Grid and Package Networks [PDF]
, 2008 One of the most crucial high performance systems-on-chip design challenge is to front their power supply noise sufferance due to high frequencies, huge number of functional blocks and technology scaling down.
Casu +10 more
core +1 more source