Results 141 to 150 of about 15,562,972 (297)

Identifying and characterising a plant GH1 β‐glucosidase that exhibits hydrolytic activity on N‐linked glucopyranoside

FEBS Open Bio, EarlyView.
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli, Carlotta Chiesa, Maher Abou Hachem, Ditte Hededam Welner   +3 more
wiley   +1 more source

Time-Specific Thresholds for Batch Process Monitoring: A Study Based on Two-Dimensional Conditional Variational Auto-Encoder

This paper studies the use of varying threshold in the statistical process control (SPC) of batch processes. The motivation is driven by how when multiple phases are implicated in each repetition, the distributions of the features behind vary with phases
Jinlin Zhu, Xuyang Lou, LOU, Xuyang, Zheng Zhang, GAO, Furong, ZHU, Jinlin, LIU, Zhong, ZHANG, Zheng, Zhong Liu, Furong Gao   +9 more
core   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

A Holistic Evaluation of Multivariate Statistical Process Monitoring in a Biological and Membrane Treatment System. [PDF]

ACS ES T Water
Newhart KB, Klanderman MC, Hering AS, Cath TY.   +3 more
europepmc   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

A Review of Data-Driven Intelligent Monitoring for Geological Drilling Processes

The exploration and development of resources and energy are fundamental to human survival and development, and geological drilling is a key method for deep resource and energy exploration.
Haipeng Fan, Sheng Du, Cheng Huang, Xian Ma   +3 more
core   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

Impact of a Quality Improvement Initiative to Reduce Medication-induced Kidney Injury. [PDF]

Pediatr Qual Saf
Stoudemire W, Akil N, Bernstein A, Bjornstad E, Cuthriell M, Damari ND, Dewalt D, Echols C, Falato C, Liao Y, Loughlin C, McKinzie C, Steiner M, Westreich K.   +13 more
europepmc   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Construction of nursing-sensitive quality indicators for hemodialysis vascular access: a Delphi study. [PDF]

Front Public Health
Zhang Y, He L, Tang S, Gao Y, Chen H, Shi M, Chen L.   +6 more
europepmc   +1 more source