Results 91 to 100 of about 4,377,183 (301)

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Aplikasi Seven Tools untuk Mengurangi Cacat Produk White Body pada Mesin Roller

open access: yesJurnal Sistem dan Manajemen Industri, 2018
This study aims to demonstrate effectively application of the seven tools as one of the quality management tools to reduce product defects. A case study has been conducted in the production of white body at PT. XYZ, which is located in Semarang. The high
Tio Prima Matondang   +1 more
doaj   +1 more source

Accurate Estimation of Gaseous Strength using Transient Data

open access: yes, 2011
Information about the strength of gas sources in buildings has a number of applications in the area of building automation and control, including temperature and ventilation control, fire detection and security systems.
Kar, Swarnendu, Varshney, Pramod K.
core   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Application of statistical methods in the control of technological beer production

open access: yesНовые технологии, 2019
The article analyzes the factors forming the quality of beer, which is produced at one of the enterprises in the Omsk region. Their influence on the main characteristics of the manufactured product is also determined. It has been found that raw materials
I. Y. Gorlova   +3 more
doaj   +1 more source

CRN5EXP: Expert system for statistical quality control [PDF]

open access: yes
The purpose of the Expert System CRN5EXP is to assist in checking the quality of the coils at two very important mills: Hot Rolling and Cold Rolling in a steel plant.
Hentea, Mariana
core   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

open access: yesMolecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli   +7 more
wiley   +1 more source

Prerequisites for Statistical Analyses of the Quality of Instrument Flight Procedures

open access: yesPromet (Zagreb)
Instrument flight procedures are essential and critical components of the global aviation system. They are designed for all phases of flight, i.e.  the standard instrument departures, standard instrument arrivals, instrument approaches and the en-route ...
Roman Romanović   +2 more
doaj   +1 more source

CONTROL ORGANIZATION OF TECHNOLOGICAL PROCESSES OF RAILWAY STATIONS ON THE BASIS OF STATISTICAL METHODS

open access: yesNauka ta progres transportu, 2019
Purpose. The article is aimed to develop statistical methods for monitoring the technological processes of railway stations` operation based on Stewhart charts. Methodology.
D. M. Kozachenko   +2 more
doaj   +1 more source

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