Results 61 to 70 of about 1,897,301 (307)

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Evaluation of indices for the measurement of quality in health systems

International Journal of Metrology and Quality Engineering, 2016
In recent decades different numeric indicators and methods have been used to qualify structured index that express health service components quality performance.
Clemente Fabrizio, Papi Marco, Pontecorvi Luca, Menichetti Antonio   +3 more
doaj   +1 more source

Um método simples para o projeto ótimo de gráficos de X A simple method for optimal X-chart design

Gestão & Produção, 1998
É desenvolvido um método simples e eficiente para a seleção de parâmetros (tamanho de amostra, intervalo de tempo entre amostras, e largura dos limites de controle) para gráficos de para controle estatístico de processos, que fornece soluções ótimas em ...
Eugenio K. Epprecht, Alessandra Bastos dos Santos   +1 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Statistical Quality Control of Microarray Gene Expression Data [PDF]

Journal of Systemics, Cybernetics and Informatics, 2011
This paper is about how to control the quality of microarray expression data. Since gene-expression microarrays have become almost as widely used as measurement tools in biological research, we survey microarray experimental data to see possibilities and
Shen Lu, Richard S. Segall
doaj  

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Statistical quality control : Using Excel

, 1999
Statistical Quality Control: Using Excel by Steven M. Zimmerman and forgery Marjorie L. Icenogel is reviewed.
Klefsjö, Bengt,
core  

ANALISIS PENGENDALIAN CACAT PRODUK TELUR AYAM MENGGUNAKAN STATISTICAL QUALITY CONTROL DI BRAM FARM

E-Jurnal Matematika
This study aims to analyze the quality control of chicken egg production at Bram Farm by applying Statistical Quality Control (SQC) tools to identify the level and types of defects that occur during the production process. Quantitative data were obtained
EVA KOSASIH, ALEN VIKTORIA BRIA, NI NYOMAN AYU NIRMALA LUKITA, NI PUTU SINTYA ARTA DEWI, MADE AYU DWI OCTAVANNY   +4 more
doaj   +1 more source