Results 111 to 120 of about 1,393,343 (316)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Factors of Self-Care Agency in Patients with Inflammatory Bowel Disease in Japan

open access: yesInflammatory Intestinal Diseases
Introduction: Currently, no self-care measurement tool specific to inflammatory bowel disease (IBD) exists in Japan. The Instrument for Diabetes Self-care Agency (IDSCA) is a reliable and valid self-care measurement tool for patients with diabetes ...
Hikaru Mizuno   +5 more
doaj   +1 more source

iMethylK_pseAAC: Improving Accuracy of Lysine Methylation Sites Identification by Incorporating Statistical Moments and Position Relative Features into General PseAAC via Chou’s 5-steps Rule

open access: yesCurrent Genomics, 2019
Background: Methylation is one of the most important post-translational modifications in the human body which usually arises on lysine among the most intensely modified residues.
Sarah Ilyas   +5 more
semanticscholar   +1 more source

Impact of a senior research thesis on students' perceptions of scientific inquiry in distinct student populations

open access: yesFEBS Open Bio, EarlyView.
This study addressed how a senior research thesis is perceived by undergraduate students. It assessed students' perception of research skills, epistemological beliefs, and career goals in Biochemistry (science) and BDC (science‐business) students. Completing a thesis improved confidence in research skills, resilience, scientific identity, closed gender‐
Celeste Suart   +4 more
wiley   +1 more source

Sound insulation of lightweight partition walls with regard to structural sound transmission

open access: yesMATEC Web of Conferences, 2018
The known methods of acoustical calculation in buildings disregard the phenomenon of structural sound transmission, whereas its effect can reach from 2 to 12 dB.
Lelyuga Olga, Ovsyannikov Sergey
doaj   +2 more sources

Psychometric Properties of Persian Version of the Multidimensional Body-Self Relations Questionnaire (MBSRQ) Among Iranian Elderly

open access: yesSālmand, 2020
Objectives: This research aimed to investigate the psychometric properties of the Persian version of the Multidimensional Body-Self Relations Questionnaire (MBSRQ) among older Iranian people.
Hashem Shemshadi   +5 more
doaj  

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

open access: yesFEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru   +6 more
wiley   +1 more source

Psychometric Properties of Self-Regulating Climate Questionnaire [PDF]

open access: yesIranian Evolutionary Educational Psychology Journal, 2020
The study sought to determine the psychometric properties of self -regulatory climate questionnaire among Iranian students as well as comparing the self- regulatory climate in Gifted and Public Schools.
Roohollah Saranjam
doaj  

Complexity of waves in nonlinear disordered media

open access: yes, 2010
The statistical properties of the phases of several modes nonlinearly coupled in a random system are investigated by means of a Hamiltonian model with disordered couplings.
Conti, Claudio, Leuzzi, Luca
core   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

open access: yesFEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida   +6 more
wiley   +1 more source

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