Results 111 to 120 of about 8,661,639 (296)

Open-Source Statistical Software: Revolutionising Health Research

open access: yesJournal of the Pakistan Medical Association
Data are everywhere, and medical and public healthresearch depends on making sense of it. This requiresutilisation of advanced statistical and geographicalinformation system (GIS) tools to glean insights from data,guide health and public policies, and ...
Masood Ali Shaikh, Syed Muhammad Mubeen
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

Using autonomous components to improve runtime qualities of software

open access: yes, 2011
In the development of software systems, quality properties should be considered along with the development process so that the qualities of software systems can be inferred and predicted at the specification and design stages and be evaluated and ...
Jiao, W., W. Jiao
core   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Electronic Dissemination of Statistical Data [PDF]

open access: yes
The Subcommittee on Electronic Dissemination of Statistical Data was formed in January 1994 to document the use in Federal statistical agencies of electronic means of disseminating data.
United States, Federal Committee on Statistical Methodology. Subcommittee on Electronic Dissemination of Statistical Data
core   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

INPUT MODELLING USING STATISTICAL DISTRIBUTIONS AND ARENA SOFTWARE [PDF]

open access: yesAnnals: Series on engineering sciences (Academy of Romanian Scientists), 2015
The paper presents a method of choosing properly the probability distributions for failure time in a flexible manufacturing system. Several well-known distributions often provide good approximation in practice.
Elena Iuliana GINGU (BOTEANU)   +1 more
doaj  

Home - About - Disclaimer - Privacy