Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn +4 more
wiley +1 more source
The influence of different digital registration methods on measurement accuracy of clear aligner treatment outcomes. [PDF]
Adel SM +4 more
europepmc +1 more source
Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source
A Pathway for Improving Performance and Interpretation of Strain in a Pediatric Echocardiography Laboratory. [PDF]
Patel S +4 more
europepmc +1 more source
Click-qPCR: A Simple Tool for Interactive qPCR Data Analysis. [PDF]
Kubota A, Tajima A.
europepmc +1 more source
Pv3Rs: Plasmodium vivax relapse, recrudescence, and reinfection statistical genetic inference. [PDF]
Foo YS, White MT, Taylor AR.
europepmc +1 more source
Appraisal on the indications, subtypes, and complications of surgically treated thyroid diseases for thyroidologists: A systematic review and meta-analysis in thyroidology. [PDF]
Sengul I, Sengul D.
europepmc +1 more source
Targeting Piezo1 can improve endometrial fibrosis by inhibiting ferroptosis in endothelial cells. [PDF]
Yang H +8 more
europepmc +1 more source
Accuracy and reliability of Manus, ChatGPT, and Claude in case-based dental diagnosis. [PDF]
Madfa AA +4 more
europepmc +1 more source

