Results 121 to 130 of about 9,557,807 (384)
Molecular Oncology, EarlyView.We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau +11 more
wiley +1 more source
Understanding Power and Rules of Thumb for Determining Sample Sizes [PDF]
Tutorials in Quantitative Methods for Psychology, 2007 This article addresses the definition of power and its relationship to Type I and Type II errors. We discuss the relationship of sample size and power.
Betsy L. Morgan +1 more
doaj
Molecular Oncology, EarlyView.Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit +19 more
wiley +1 more source
Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry
Molecular Oncology, EarlyView.Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson +11 more
wiley +1 more source
Tutorials in Quantitative Methods for Psychology, 2007 One possible reason for the continued neglect of statistical power analysis in research in the behavioral sciences is the inaccessibility of or difficulty with the standard material.
Jacob Cohen
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The effect on cosmological parameter estimation of a parameter dependent covariance matrix
The Open Journal of Astrophysics, 2019 Cosmological large-scale structure analyses based on two-point correlation functions often assume a Gaussian likelihood function with a fixed covariance matrix. We study the impact on cosmological parameter estimation of ignoring the parameter dependence
Darsh Kodwani +2 more
doaj +1 more source
A Note on the Eigenvalue Problem in Crystal Statistics [PDF]
, 1950 Yasusada Nambu
openalex +1 more source
Molecular Oncology, EarlyView.Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu +11 more
wiley +1 more source
Wanted Dead or Alive? The tradeoff between in-vivo versus ex-vivo MR brain imaging in the mouse.
Frontiers in Neuroinformatics, 2012 High resolution MRI of the mouse brain is gaining prominence in estimating changes in neuroanatomy over time to understand both normal developmental as well as disease processes and mechanisms.
Jason P Lerch +9 more
doaj +1 more source