Results 121 to 130 of about 8,829,811 (310)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

The Road Not Taken: Misclassifying an Anti‐Seizure Medication as a Failure

open access: yesAnnals of Clinical and Translational Neurology
Objective To quantify how often anti‐seizure medications (ASMs) appear ineffective yet provide benefit when considering seizure frequency (SF) variability. Methods We used the CHOCOLATES seizure diary simulator to generate 100,000 patient seizure diaries
Christopher N. Henry   +1 more
doaj   +1 more source

Substantiation of Estimation Methods of Technogenic Noise Impact in Cadastral Value Determination of Land Plots

open access: yesLand
This article presents a substantiation of methods for assessing the impact of anthropogenic noise pollution for land taxation. Statistical analyses have been carried out in order to establish the dependence of the market value of land plots for ...
Elena Bykowa, Ivan Raguzin
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Certification Can Count: The Case of Aircraft Mechanics [PDF]

open access: yes, 2002
[Excerpt] In 2000, aircraft mechanics and service technicians certified by the Federal Aviation Administration (FAA) earned on average $20.16 per hour. Aircraft mechanics and technicians without FAA certification earned on average $15.78 per hour, over ...
Bureau of Labor Statistics
core   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Corpus Interpretation of English Ecological Discourse: Linguistic Regularities and Functional Features

open access: yesВиртуальная коммуникация и социальные сети
English-language environmental speech has its own linguistic features. Ecological discourse is a relevant, self-sufficient, and highly identical communication continuum.
Aleksandr A. Barkovich
doaj   +1 more source

Home - About - Disclaimer - Privacy