Results 51 to 60 of about 8,240,563 (383)
Coastal lagoons are one of the most threatened ecosystems in the world, because of population growth, habitat destruction, pollution, wastewater, overexploitation and invasive species which are the main causes of their degradation.
Ildefonso Baldiris-Navarro+4 more
doaj +1 more source
Human colon organoid differentiation from induced pluripotent stem cells using an improved method
We compared established protocols to differentiate induced pluripotent stem cells into colon organoids and found that activation of bone morphogenetic protein 2 signaling induced gene expression of colon‐specific markers. Adenovirus‐mediated transduction of the transcription factors HOXD13 or SATB2 further enhanced colonic gene expression, suggesting ...
I‐Ting Lee+4 more
wiley +1 more source
The Statistics Consortium at the University of Maryland, College Park, hosted a two-day workshop on Bayesian Methods that Frequentists Should Know during April 30--May 1, 2008. The event was co-sponsored by the Institute of Mathematical Statistics (IMS), Office of Research and Methodology, National Center for Health Statistics, Survey Research Methods ...
arxiv +1 more source
ONLINE STATISTICS SYSTEM FOR PARTICIPANTS IN THE DISCORD MESSENGER USING PYTHON AND POSTGRESQL
The relevance of the topic under consideration is since in one of the Discord channel communities there was a need to collect the activity of channel members for a certain time and duration.
Roman R. Krapivin+3 more
doaj +1 more source
Statistical evidence is crucial throughout disparate impact’s three-stage analysis: during (1) the plaintiff’s prima facie demonstration of a policy’s disparate impact; (2) the defendant’s job-related business necessity defense of the discriminatory ...
Tobia, Kevin P.
core +1 more source
Hermansky‐Pudlak syndrome type 1 (HPS‐1) is a rare, autosomal recessive disorder with poorly understood renal involvement. Urinary extracellular vesicle (uEV) proteomics and a novel Hps1 mouse model reveal mitochondrial abnormalities and lipid accumulation in HPS‐1 kidney proximal tubule cells. Serum ApoA1 correlates with kidney function in our patient
Dawn M. Maynard+7 more
wiley +1 more source
We describe a novel set of Epac‐based FRET‐FLIM biosensors with improved fully cytosolic distribution, achieved without compromising the state‐of‐the‐art performance of our original designs, for detecting cAMP dynamics in real time in live cells with high precision and reliability.
Giulia Zanetti+2 more
wiley +1 more source
The Statistics of q-Statistics
Almost two decades ago, Ernesto P. Borges and Bruce M. Boghosian embarked on the intricate task of composing a manuscript to honor the profound contributions of Constantino Tsallis to the realm of statistical physics, coupled with a concise exploration of q-Statistics.
Deniz Eroglu+3 more
openaire +3 more sources
Fisher's combined probability test for high-dimensional covariance matrices [PDF]
Testing large covariance matrices is of fundamental importance in statistical analysis with high-dimensional data. In the past decade, three types of test statistics have been studied in the literature: quadratic form statistics, maximum form statistics, and their weighted combination.
arxiv
We explore 5HT2A receptor activation, a key target for psychedelic drugs, using molecular dynamics simulations. Without Gqα, the active receptor collapses to an inactive conformation, underscoring the G‐protein's role. Discovery of an intermediate “partially‐open” state and the higher affinity of ligands to the orthosteric binding site provides ...
Niklas Viohl+2 more
wiley +1 more source