NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks +4 more
wiley +1 more source
Comparison of classification models for adolescent's emotional and behavioral problems. [PDF]
Tilyeubai A +8 more
europepmc +1 more source
ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function
Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley +5 more
wiley +1 more source
Response to "Sample Representativeness and Test-Retest Reliability in the Japanese Everyday Ageism Scale: A Methodological Reconsideration". [PDF]
Kawaguchi K +4 more
europepmc +1 more source
Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito +7 more
wiley +1 more source
Exponent Spectrum of Lorenz Curves and Its Relation to a System's Heterogeneity. [PDF]
Das S, Biswas S.
europepmc +1 more source
Assessing the effects of limited vaccine supply on risk-based vaccination strategies in regions of endemic foot-and-mouth disease. [PDF]
Guyver-Fletcher G, Tildesley M.
europepmc +1 more source
Rainfall frequency and uncertainty analysis in arid regions using machine learning and statistical distribution models based on a 91-year rainfall record. [PDF]
Hagage M.
europepmc +1 more source
Rapid value learning reveals generalized and context-dependent codes in frontal cortex
Gutierrez E +6 more
europepmc +1 more source

