Results 151 to 160 of about 813,688 (256)

Fast and Rigorous Computation of Gene and Pathway Scores from SNP-Based Summary Statistics

, 2016
David Lamparter, Daniel Marbach, Rico Rueedi, Zoltán Kutalik, Sven Bergmann   +4 more
openalex   +2 more sources

Nonextensive statistics: theoretical, experimental and computational evidences and connections [PDF]

, 1999
Constantino Tsallis
openalex   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

LIST OF AUTHORS AND TITLES INTERNATIONAL CONFERENCE ON NEW TRENDS IN COMPUTATIONAL STATISTICS WITH BIOMEDICAL APPLICATIONS (ICNCB)

, 2001
Y Tanaka, S Azen, T Shohoji, J Niland, J Jones, D Stahl, M Nichol, A Hayashi, M Rocca, T Koshimizu, M Tsujitani   +10 more
openalex   +2 more sources

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Investigation of Combined Toxic Metals, PFAS, Volatile Organic Compounds, and Essential Elements in Chronic Kidney Disease. [PDF]

J Xenobiot
Adetunji AG, Obeng-Gyasi E.
europepmc   +1 more source

Abstracts of Bulletin of The Computational Statistics of Japan, Vol 4, No. 1, 1991

, 1991

openalex   +2 more sources

Computational statistics: a teaching approach

, 2020
Isabel Quintas Pereiras, Departamentos de Política y Cultura y Producción Económica, UAM Xochimilco   +1 more
openalex   +2 more sources

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

FastCCC: a permutation-free framework for scalable, robust, and reference-based cell-cell communication analysis in single cell transcriptomics studies. [PDF]

Nat Commun
Hou S, Ma W, Zhou X.
europepmc   +1 more source