Results 271 to 280 of about 2,065,553 (347)

Facilitating crRNA Design by Integrating DNA Interaction Features of CRISPR‐Cas12a System

open access: yesAdvanced Science, EarlyView.
This study introduces a novel approach combining molecular dynamics simulations and neural network modeling to predict the Cas12a trans‐cleavage activity. By integrating sequence and molecular interaction features, prediction accuracy is enhanced, and identify key features affecting Cas12a trans‐cleavage activity.
Zhihao Yao   +7 more
wiley   +1 more source

Proteomics‐Empowered Microfluidic‐SERS Immunoassay for Identifying and Detecting Biomarkers of Micropapillary Lung Adenocarcinoma

open access: yesAdvanced Science, EarlyView.
The presence of a micropapillary (MPP) component is critical for lung adenocarcinoma (LUAD) surgery, yet reliable blood biomarkers remain lacking. This study integrates proteomics for biomarker identification, a nanomixing‐enhanced surface‐enhanced Raman spectroscopy (SERS) platform for sensitive detection, and machine learning for accurate ...
Dechun Zhang   +4 more
wiley   +1 more source

Machine learning identifies genes linked to neurological disorders induced by equine encephalitis viruses, traumatic brain injuries, and organophosphorus nerve agents. [PDF]

open access: yesFront Comput Neurosci
Yin L   +9 more
europepmc   +1 more source

When the whole is greater than the sum of its parts: why machine learning and conventional statistics are complementary for predicting future health outcomes

open access: gold
Roemer J. Janse   +8 more
openalex   +1 more source

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