Results 41 to 50 of about 1,371,617 (304)

Data Complexity in Machine Learning and Novel Classification Algorithms [PDF]

open access: yes, 2006
This thesis summarizes four of my research projects in machine learning. One of them is on a theoretical challenge of defining and exploring complexity measures for data sets; the others are about new and improved classification algorithms.
Li, Ling
core   +1 more source

Online Learning for Statistical Machine Translation [PDF]

open access: yesComputational Linguistics, 2016
We present online learning techniques for statistical machine translation (SMT). The availability of large training data sets that grow constantly over time is becoming more and more frequent in the field of SMT—for example, in the context of translation agencies or the daily translation of government proceedings.
openaire   +2 more sources

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett   +8 more
wiley   +1 more source

Logistic model trees

open access: yes, 2005
Tree induction methods and linear models are popular techniques for supervised learning tasks, both for the prediction of nominal classes and numeric values.
Hall, Mark A.   +2 more
core   +1 more source

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling   +16 more
wiley   +1 more source

Machine Learning and Statistical MAP Methods [PDF]

open access: yes, 2006
For machine learning of an input-output function f from examples, we show it is possible to define an a priori probability density function on the hypothesis space to represent knowledge of the probability distribution of f, even when the hypothesis space H is large (i.e., nonparametric).
Mark A. Kon   +2 more
openaire   +1 more source

Automatic robust estimation for exponential smoothing: Perspectives from statistics and machine learning

open access: yesExpert systems with applications, 2020
A major challenge in automating the production of a large number of forecasts, as often required in many business applications, is the need for robust and reliable predictions.
Devon K. Barrow   +3 more
semanticscholar   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu   +21 more
wiley   +1 more source

Copula models in machine learning [PDF]

open access: yes, 2015
The introduction of copulas, which allow separating the dependence structure of a multivariate distribution from its marginal behaviour, was a major advance in dependence modelling.
Rey, Mélanie
core   +1 more source

Longitudinal Assessment of Biomarkers in ALS: Discriminative Biomarkers for Disease Progression and Survival

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To assess the association and discriminative performance of serum biomarkers with clinical disease progression and survival in patients with amyotrophic lateral sclerosis (ALS). Methods This retrospective study, conducted at Houston Methodist Hospital, Houston, TX, used longitudinal serum samples collected between January 2018 and ...
David R. Beers   +7 more
wiley   +1 more source

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