Results 191 to 200 of about 890,957 (263)

Evaluation of Digital Technologies for Home‐Based Assessment in People With Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Digital technologies hold promise for transforming healthcare by enhancing personalized treatments and offer valuable opportunities to improve patient care. Here, we evaluated several novel, self‐administered, home‐based, digital endpoints for their association with corresponding conventional standard clinical measures (primary) in ...
Arne Mueller, Vanessa Vallejo, Mónica Povedano Panadés, Orla Hardiman, Véronique Danel‐Brunaud, Senda Ajroud‐Driss, Philippe Couratier, Jeremy Shefner, Anna Gokey, Mike DiCesare, Erin Lennox, Jens Praestgaard, Lucie Brujin, Peggy Allred, Ram Miller   +14 more
wiley   +1 more source

AI and clinicians growing together: A cross-sectional survey of clinicians' attitudes toward AI-CDSS with comparison to 2020 data. [PDF]

Clin Med (Lond)
Curiello S, Chapman A, Wyatt JC.
europepmc   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw, Karishma Randhave, Ekta Anand, Ziang (Debbie) Song, Wangzhen Shen, Jing‐Qiong Kang   +5 more
wiley   +1 more source

Promoting structural sustainable design through the influence of quality control assessments. [PDF]

Sci Rep
Lux T, Feiri T, Schulze-Ardey JP, Hegger J, Claßen M, Ricker M.   +5 more
europepmc   +1 more source

White Matter Microstructural Abnormalities in Neonatal Onset Genetic Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Recent evidence indicates that epilepsy is associated with abnormal white matter. If seizures alter white matter, then the impact upon network function, epileptogenesis, and cognition could be pronounced in neonates undergoing rapid developmental myelination. Neonates with epilepsy due to nonstructural genetic causes provide a unique
Amanda G. Sandoval Karamian, Tianjia Zhu, Hao Huang, Shavonne L. Massey, Mark P. Fitzgerald, Darshana Parikh, Arastoo Vossough, Ingo Helbig, Nicholas S. Abend   +8 more
wiley   +1 more source

Upper Cervical Cord Area as a Biomarker of Conversion to Secondary Progressive Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study assessed whether upper cervical cord area (UCCA) measured on routine brain MRI can serve as a biomarker of conversion to SPMS. Methods This is a single‐center retrospective cohort study of RRMS patients with cross‐sectional and longitudinal analyses of clinical and MRI data. Future SPMS converters were matched by age, sex,
Nabil K. El Ayoubi, Sola Al Ghazal, Salem Hannoun, Medhat A. Siddik, Nour M. Najjar, Jim Dagher, Joseph Abboud, Myriam G. Semaan, Samia J. Khoury   +8 more
wiley   +1 more source

Draft genome sequence of <i>Virgibacillus salarius</i> isolated from the San Juan Hypersaline Lagoon, Chihuahua, Mexico. [PDF]

Microbiol Resour Announc
Cruz-Soto AS, Hernández-Peña CC, Soto-Padilla MY, Laredo-Tiscareño SV, Gonzalez Peña R, de Jesús de Luna-Santillana E, Cira-Chávez LA, Garza-Hernández JA.   +7 more
europepmc   +1 more source

Risk Factors for Dysfunctional Liver Graft Response: A Case-Control Study. [PDF]

Nurs Health Sci
Cavalcante LP, Neto JC, Alves MBF, da Cunha FAP, Gomes ACB, Barreiro RG, da Silva VM, Lopes MVO.   +7 more
europepmc   +1 more source

StrucPTM: a database of structurally validated protein modifications and their conformational variation. [PDF]

Bioinformatics
Jeon SG, Yoo J, Joo K, Paek E.
europepmc   +1 more source