Results 151 to 160 of about 3,048,047 (361)

Neuid: A Novel Neuron‐Enriched LncRNA that Connects Epigenetic Gene Silencing to Alzheimer's Disease

open access: yesAdvanced Science, EarlyView.
ABSTRACT The increasing evidence that non‐coding RNAs can become deregulated during pathogenesis is dramatically expanding the space for drug discovery beyond the protein‐coding genome. Long noncoding RNAs (lncRNAs) are emerging as key regulators of cellular function, yet most remain uncharacterized.
Ranjit Pradhan   +17 more
wiley   +1 more source

Helping Alleviate Statistical Anxiety with Computer Aided Statistics Classes

open access: yesJournal of the Scholarship of Teaching and Learning, 2007
John Stickels, Rhonda Dobbs
doaj   +2 more sources

Shared Care Dyadic Intervention: Outcome Patterns for Heart Failure Care Partners [PDF]

open access: yes, 2012
Up to half of heart failure (HF) patients are readmitted to hospitals within 6 months of discharge. Many readmissions are linked to inadequate self-care or family support.
Sebern, Margaret, Woda, Aimee
core   +2 more sources

CRP Deficiency Rescues Periodontitis‐Induced Hippocampal Neurogenesis Impairment by Suppressing OPC‐Derived BMP4 Signaling in Rats

open access: yesAdvanced Science, EarlyView.
Chronic periodontitis elevates circulating CRP, which enters the hippocampus to upregulate BMP4 in oligodendrocyte precursor cells (OPCs), thereby impairing neurogenesis and inducing anxiety/depression‐like behaviors in rats. Counteracting this pathway, CRP deficiency helps confer functional resilience to OPCs.
Lingjie Li   +9 more
wiley   +1 more source

A Tac1‐Expressing Brainstem Pathway Underlies the Pathogenesis of Trigeminal Neuralgia

open access: yesAdvanced Science, EarlyView.
A critical TG‐Sp5CTac1‐PBNTac1 pathway drives trigeminal neuropathic pain (TNP). Tac1‐expressing parabrachial nucleus (PBNTac1) neurons exhibit heightened responses to innocuous stimuli in TNP, and chemogenetic inhibition of these neurons effectively prevents TNP development.
Liting Sun   +11 more
wiley   +1 more source

An absence of attentional bias: statistics anxiety is unique among anxieties

open access: yes, 2016
The first purpose of the project was to examine the internal consistency and structure of the English version of the Statistical Anxiety Rating Scale (STARS). Participants were 202 (79% females) psychology undergraduates at James Cook University. Participants completed the STARS, the Statistical Anxiety Scale, and the Attitudes toward Statistics scale.
openaire   +2 more sources

Fibronectin1‐Expressing Subicular Circuits Selectively Govern the Retrieval of Novel Object Recognition

open access: yesAdvanced Science, EarlyView.
Fibronectin 1 (FN1)‐expressing subicular subpopulations encode novel object preference and selectively govern retrieval of novel object recognition (NOR) via affecting excitability of entorhinal‐projecting circuit through large conductance Ca2+‐activated potassium (BK) channel. ABSTRACT Novel object recognition (NOR), referring to the cognitive ability
Fan Fei   +15 more
wiley   +1 more source

Thermally Degradable Biocompatible Hydrogel as Transient Encapsulation Coating for Implantable Sensors

open access: yesAdvanced Science, EarlyView.
A biocompatible hydrogel coating with tissue‐like mechanics and reversible dissolution triggered by a mild, physiologically compatible temperature drop (≈37°C → ≈25°C) was developed for the transient encapsulation of implantable devices. The physically crosslinked methylcellulose, polyethylene glycol and polyacrilic acid (MC/PEG/PAA) hydrogel ...
Francesca Persano   +14 more
wiley   +1 more source

STATISTICS ANXIETY AMONG MEDICAL PROFESSIONALS IN DEVELOPING COUNTRIES: PROBLEMS AND WAY FORWARD

open access: yesKhyber Medical University Journal, 2017
Medical professionals need statistical acumen for research management. Evidence-based practice of bio-statistics guides researchers to correctly apply different statistical techniques.1 It helps in correct interpretation of results, making right ...
Aamir Abbas, Akhtar Sherin
doaj  

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