Results 271 to 280 of about 3,048,047 (361)
A preclinical mouse model mimicking the ovarian cancer‐induced estrogen deficiency‐depression axis
A preclinical mouse model of ovarian cancer–related depression was developed by combining intraperitoneal tumor cell injection, ovariectomy, and chronic restraint stress. The model replicates key clinical features including estrogen deficiency, depressive‐like behaviors, and tumor progression, and provides a reliable tool for studying the endocrine ...
Jiamin Liu +6 more
wiley +1 more source
Scalp electroacupuncture (SA) through activation of the trigeminal pathway exerts anti‐inflammatory, antidepressant, and anxiolytic effects in an animal model of post‐traumatic stress disorder induced by single prolonged stress. This suggests that SA is involved in neuroinflammation and changes in brain‐derived neurotrophic factor protein through the ...
Bombi Lee +3 more
wiley +1 more source
Flourishing older Canadians: What characteristics are associated with complete mental health? [PDF]
Rahim D +3 more
europepmc +1 more source
The pathogenesis of stress urinary incontinence (SUI) is intimately associated with injury to the external urethral sphincter (EUS). In this study, we established an SUI model induced by double vaginal distension and demonstrated that metformin treatment activated the AMPK signaling in the EUS tissue.
Yuting Xu +7 more
wiley +1 more source
P5 Mental Health Platform: A Digital Solution to Monitor Anxiety and Depression Symptoms in the General Portuguese Population. [PDF]
Soares-Coelho P +6 more
europepmc +1 more source
Distinct Prescription Patterns Emerge Years Before ALS Diagnosis: A Nationwide Registry‐Based Study
Objective The prodromal phase of amyotrophic lateral sclerosis (ALS) is poorly defined. We aimed to characterize prescription drug use patterns in the pre‐diagnostic period by analyzing nationwide prescription data to identify the earliest divergence between individuals who developed ALS and matched healthy controls.
Magne Haugland Solheim +6 more
wiley +1 more source
Relationships among athletes' challenge and threat perceptions, mindfulness, and anxiety. [PDF]
Karademir MB +6 more
europepmc +1 more source

