Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface
FEBS Open Bio, EarlyView.HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana +5 more
wiley +1 more source
National Vital Statistics System Division of Vital Statistics Newsletter ;\ua0June 2020
nside this issue \u2013 Updates on the upcoming Vital Records and Their Administration: Statistics and Data Quality Course (virtual); release of the 2019 Provisional Birth Data and the 2018 Linked Birth and Infant Death Data; maternal COVID-19 and birth ...
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Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription
FEBS Open Bio, EarlyView.In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang +10 more
wiley +1 more source
National Vital Statistics System Division of Vital Statistics newsletter ; September 2022
Inside this issue \u2013 Information regarding the upcoming October 2022 VSCP Directors Webinar; Vital Statistics Modernization Community of Practice information on the Health Information and Management Systems Society Interoperability Showcase that will
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Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model
FEBS Open Bio, EarlyView.This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito +7 more
wiley +1 more source
Editorial: Methods for imaging and omics data science: advances, applications, and spatiotemporal innovations. [PDF]
Front GenetMallick H +7 more
europepmc +1 more source
National Vital Statistics System Division of Vital Statistics newsletter ; December 2022
Inside this issue \u2013 Information regarding the upcoming January 2022 VSCP Directors Webinar; Notable publication information on changes in twin births in the United States; Information on the 2022 data year close-out; Vital Statistics Modernization ...
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Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA
FEBS Open Bio, EarlyView.Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley +1 more source
Reddit Discussions During the 2022 Mpox Outbreak: Observational Analysis of Sentiment, Topics, and Audience Engagement. [PDF]
J Med Internet ResLuo XN, Movahedi Nia Z, Kong JD.
europepmc +1 more source
National Vital Statistics System Division of Vital Statistics newsletter ; March 2023
Inside this issue \u2013 Information regarding the New Medicolegal Death Investigation FHIR Implementation Collaborative; Notable publication information on Maternal and Infant Characteristics and Outcomes Among Women with Confirmed or Presumed COVID-19 ...
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