Results 51 to 60 of about 1,692,958 (373)

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

open access: yesFEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer   +7 more
wiley   +1 more source

Secondary Sources: Top Ten [PDF]

open access: yes, 2005
Secondary sources are a legal researcher\u27s best friend. They are a great place to begin researching a new topic as they provide a framework for understanding the subject.
Zago, Susan Drisko
core   +1 more source

Directions and projective shapes

open access: yes, 2005
This paper deals with projective shape analysis, which is a study of finite configurations of points modulo projective transformations. The topic has various applications in machine vision.
Mardia, Kanti V., Patrangenaru, Vic
core   +1 more source

Maximally selected chi-square statistics for at least ordinal scaled variables [PDF]

open access: yes, 2005
The association between a binary variable Y and a variable X with an at least ordinal measurement scale might be examined by selecting a cutpoint in the range of X and then performing an association test for the obtained 2x2 contingency table using the ...
Boulesteix, Anne-Laure
core   +2 more sources

Modeling Topics in DFA-Based Lemmatized Gujarati Text

open access: yesSensors, 2023
Topic modeling is a machine learning algorithm based on statistics that follows unsupervised machine learning techniques for mapping a high-dimensional corpus to a low-dimensional topical subspace, but it could be better.
Uttam Chauhan   +9 more
doaj   +1 more source

Vacuolar transport and function of Saccharomyces cerevisiae sterol ester hydrolase Tgl1

open access: yesFEBS Letters, EarlyView.
Tgl1, one of yeast sterol ester hydrolases, had been found on the lipid droplets where sterol esters are mainly stored. This study revealed that Tgl1 is transported into the vacuole depending on the ESCRT‐I–III complex, and that it exhibits intra‐vacuolar sterol ester hydrolase activity.
Takumi Nakatsuji   +5 more
wiley   +1 more source

From A to Z: Asymptotic expansions by van Zwet [PDF]

open access: yes, 1999
Refinements of first-order asymptotic results are reviewed, with a number of Ph.D. projects supervised by van Zwet serving as stepping stones. Berry-Esseen bounds and Edgeworth expansions are discussed for $R$-, $L$- and $U$-statistics.
Albers, W.
core   +1 more source

Full journal publication of abstracts presented at the Nordic Congress of General Practice in 2009 and 2011

open access: yesScandinavian Journal of Primary Health Care, 2017
Objective: To determine the overall publication rates for abstracts presented at two consecutive Nordic Congresses of General Practice and to evaluate determinants for these publication rates. Design: Prospective study.
Frans Boch Waldorff   +5 more
doaj   +1 more source

Statistics for Immunologists

open access: yesCurrent Protocols in Immunology, 2018
Statistical tests and graphs are an important part of any immunological research publication or presentation, but not all immunologists have the statistical expertise to choose the best methods to evaluate and represent their experiments. These protocols
J. Skinner
semanticscholar   +1 more source

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

open access: yesFEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

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