Results 111 to 120 of about 316,216 (289)

Long‐term impact of Elexacaftor/Tezacaftor/ivacaftor on pulmonary, nutritional and metabolic outcomes in homozygous F508del cystic fibrosis patients: A real‐world cohort study

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim Elexacaftor/tezacaftor/ivacaftor (ETI) has markedly improved cystic fibrosis (CF) outcomes. However, its long‐term impact on nutrition, metabolism and liver health remains underexplored. We assessed 30‐month changes in pulmonary, nutritional, metabolic and inflammatory markers in people with CF (PwCF) homozygous for F508del.
Nicola Perrotta   +5 more
wiley   +1 more source

The Double African Paradox: What does selective mortality tell us? [PDF]

open access: yes
We study the relationship between height stature and child mortality in West Africa. This is motivated by two things: understanding the determinants of height, widely used health indicator, and explaining the « double African paradox ».
Rouanet, Léa
core  

A Growth Chart for KBG Syndrome

open access: yes
American Journal of Medical Genetics Part A, EarlyView.
Karen J. Low   +6 more
wiley   +1 more source

Unveiling student sentiment dynamics toward AI‐based education through statistical analysis and Monte Carlo simulation

open access: yesBritish Educational Research Journal, EarlyView.
Abstract This study explores the multifaceted dynamics of student sentiment towards artificial intelligence (AI)‐based education by integrating sentiment analysis techniques with statistical methods, including Monte Carlo simulations and decision tree modelling, alongside qualitative grounded theory analysis.
Volkan Duran   +2 more
wiley   +1 more source

Nineteenth Century Black and White US Statures: The Primary Sources of Vitamin D and their Relationship with Height [PDF]

open access: yes
Vitamin D is vital in all vertebrates because it allows them to absorb more calcium from their diets, contributing to stronger skeletal systems and stature growth.
Scott A. Carson
core  

Protein turnover downstream of the Nipbl/CRL4 axis contributes to abnormal development in zebrafish embryos

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background Mutations in cohesins cause cohesinopathies such as Cornelia de Lange Syndrome (CdLS) and Roberts Syndrome (RBS). Prior findings demonstrate that Esco2 (a cohesin activator) and Smc3 (a core cohesin subunit) regulate the CRL4 E3 ubiquitin ligase. SMC3 mutations, however, account for a small percentage of CdLS.
Annie C. Sanchez   +4 more
wiley   +1 more source

A globally consistent scaling relationship reveals stabilizing effects of dominant species in plant communities

open access: yesEcography, EarlyView.
Despite extensive research, stabilizing mechanisms in ecosystems remain uncertain. Taylor's power law (TPL) is a pervasive ecological pattern that describes how variance scales with mean abundance (σ2 = aμᵇ). While TPL has been widely studied within populations, its role across species within communities and its implications for stability remain ...
Clara Gracia   +33 more
wiley   +1 more source

Shifting baselines increase the risk of misinterpreting biodiversity trends

open access: yesEcography, EarlyView.
Ecological studies quantifying the impact of land‐use change on biodiversity may be sensitive to the choice of reference points – or baselines – particularly when sampling across human land‐use gradients and other space‐for‐time comparisons. Much depends on whether the chosen baseline has already undergone shifts in species composition because of ...
Ariane Dellavalle   +13 more
wiley   +1 more source

Changes in inequality and poverty in Latin America: Looking beyond income to health and education [PDF]

open access: yes
This paper uses Demographic and Health Survey data from six Latin American countries to analyze levels and trends of inequality for two important non-income measures of wellbeing, childrenz s stature and adult womenq s educational attainment. Our purpose
David E. Sahn, Stephen D. Younger
core  

Transcriptomic signatures reveal systemic adaptations and immune modulation in response to training and competitive racing in horses

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Background The molecular mechanisms underlying adaptation to physical exertion and racing stress in horses remain incompletely understood. Peripheral blood transcriptomics offers a minimally invasive method to monitor systemic responses to exercise and identify biomarkers of adaptation or overload. Objectives To evaluate transcriptomic changes
Izabela Dąbrowska   +4 more
wiley   +1 more source

Home - About - Disclaimer - Privacy