Results 191 to 200 of about 4,062,213 (266)

Recurrent Copy Number Variants and Psychiatric Outcomes in the Context of Polygenic Scores.

open access: yesJAMA Psychiatry
Vaez M   +14 more
europepmc   +1 more source

The therapeutic opportunities and pitfalls of using iron ion chelators to treat neurodegenerative diseases

open access: yesFEBS Letters, EarlyView.
Although too much iron in the brain promotes neurodegeneration, iron ion chelators have had mixed effects in clinical trials. This review explains why; some chelators do not render the iron redox‐inactive (e.g., L1) whereas others do (e.g., desferrioxamine).
Barry Halliwell
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Impact of Different Types of Sedentary Behaviour on Cognitive Function in Older Adults: A Systematic Review. [PDF]

open access: yesHealth Promot J Austr
de Jesus Silva TR   +5 more
europepmc   +1 more source

Depression and anxiety modify cognitive concerns associated with amyloid and early clinical impairment. [PDF]

open access: yesNeuropsychology
Stites SD   +5 more
europepmc   +1 more source

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