Results 101 to 110 of about 869,685 (389)

The Right to Challenge the Accuracy of Breath Test Results Under Alaska Law [PDF]

open access: yes, 2013
Section 28.90.020 of the Alaska Statutes provides that in prosecutions for drunk driving, if an offense described under this title requires that a chemical test of a person\u27s breath produce a particular result, and the chemical test is administered ...
Nilsson Bromander, Kristina   +1 more
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

A Reconsideration of the Physicians’ Immunity Statute [PDF]

open access: yes, 2001
The author assesses the physicians\u27 immunity statute from legal policy, ethical, and financial perspectives, and concludes that alternatives such as licensure and monetary incentives would better serve the goal of encouraging invention more ...
Dirksen, Steve
core   +1 more source

Drawing the boundaries of mens rea in the jurisprudence of the international criminal tribunal for the former Yugoslavia [PDF]

open access: yes, 2006
Even though more than a decade has passed since the creation of the International Criminal Tribunal for the Former Yugoslavia, the law of the most fundamental concept in international criminal law – mens rea - remains unsettled. Through its jurisprudence,
Badar, ME
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

The International Criminal Court\u27s Ineffective Enforcement Mechanisms: The Indictment of President Omar Al Bashir [PDF]

open access: yes, 2011
Part I introduces the Rome Statute and highlights the portions of the Rome Statute that leave the ICC vulnerable to member states that violate the Rome Statute without any clear punishment for the violation. In particular, Part I focuses on the expansive
Barnes, Gwen P
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Statute law or case law?. [PDF]

open access: yes
We embed a simple contracting model with ex-ante investments in which there is scope for Court intervention in a full-blown open-ended dynamic setting.
Anderlini, Luca   +2 more
core   +10 more sources

A Survey of Residual Cancer Risks Permitted by Health, Safety and Environmental Policy [PDF]

open access: yes, 1995
The authors describe permitted U.S. residual cancer risks, focusing on numerical levels specifically and implicitly authorized by statute or regulation.
Graham, John D., Sadowitz, March
core   +2 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

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