Results 111 to 120 of about 851,752 (390)

Affirming Firm Sanctions: The Authority to Sanction Law Firms Under 28 U.S.C. § 1927 [PDF]

open access: yes, 2017
A circuit split exists as to whether 28 U.S.C. § 1927 allows for an award of sanctions against nonattorneys or nonrepresentatives. Five federal courts of appeals—the Second, Third, Eighth, Eleventh, and the District of Columbia Circuits—hold that, to ...
Margiotta, Vincent J.
core   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

open access: yesMolecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir   +12 more
wiley   +1 more source

From Nuremberg to Rome and Beyond: The Fight Against Genocide, War Crimes, and Crimes Against Humanity [PDF]

open access: yes, 1999
More than 200 years ago in his work Perpetual Peace, \u27 Immanuel Kant called for peace and human rights to be protected under international law. Ever since, the United Nations, which was founded in 1945 as part of the worldwide fight against tyranny ...
Kastrup, Dieter
core   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

open access: yesMolecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He   +8 more
wiley   +1 more source

The relationship between the number of statutes coming into force and the number of regulations coming into force: Findings from empirical studies

open access: yesRuch Prawniczy, Ekonomiczny i Socjologiczny
The aim of this paper is to empirically test the opinion, common in legislative practice, that there is a relationship between the number of statutes and the number of regulations, and to measure the strength and nature of this relationship, if it ...
Patryk Ciurak
doaj   +1 more source

O PRAWNOKARNEJ OCHRONIE NASCITURUSA W III STATUCIE LITEWSKIM

open access: yesZeszyty Prawnicze, 2017
Legal and Criminal Protection of ‘nasciturus’ in the Third Lithuanian Statute Summary The Third Lithuanian Statute of 1588 regulated the issue specified in the title only partly and quite inconsistently.
Sławomir Godek
doaj   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

open access: yesMolecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson   +2 more
wiley   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

Cleaning Up the Legal Debris Left in the Wake of Whitewater [PDF]

open access: yes, 1999
We have learned a lot in the twenty-five years since Watergate. During the scandal itself, we confirmed that the President is not above the law. We learned that executive privilege is constitutionally protected, but that it is not absolute.
Bloch, Susan Low
core   +1 more source

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