Results 71 to 80 of about 869,685 (389)
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Features of corporate governance are considered. In modern realities quality of corporate governance is determined by the internal organization (accurate corporate strategy with determination of the purposes and interests of the company).
S. I. Lutsenko
doaj +1 more source
The Independent Counsel Statute: A Legal History [PDF]
Priester et al provide a comprehensive legal history of the independent counsel statute from its inception in 1978 until its apparent last hurrah in 1999. They also explore the role of the independent counsel in the history and practice of the government\
Horowitz, Mirah A. +2 more
core +2 more sources
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Time-lag i biznes. O pozaekonomicznych wyznacznikach parametrów ekonomicznych
The system of law enactment in Poland is flawed. It should be based on consultations between the government and non-governmental communities and institutions. One of the tools of such consultations, i.e.
Marek Goliszewski
doaj +1 more source
Safe-Conduct Theory of the Alien Tort Statute, The [PDF]
In this Article, Professor Lee introduces a novel explanation of the Alien Tort Statute (ATS) - a founding-era enactment that has achieved modern prominence as a vehicle for international human rights litigation.
Lee, Thomas H.
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Unnecessary Indeterminacy: Process Patent Protection After Kinik v. ITC [PDF]
In Kinik v. International Trade Commission, the U.S. Court of Appeals for the Federal Circuit suggested in dicta that the defenses available to foreign manufacturers in infringement actions under 35 U.S.C. § 271(g) in Federal district courts do not apply
Eden, John M.
core +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
The article highlights the activities of the music and choral society «Sniatyn Boian» in the town of Sniatyn in the early 20th century. The society was founded in 1900. The statute of «Sniatyn Boian» is characterized.
Андрій Королько
doaj

