Results 171 to 180 of about 3,790 (292)

When advance directives clash with family consent: designing an operational framework for end-of-life decision-making in China and Korea. [PDF]

BMC Med Ethics
Luo S, Cho D, Cho J.
europepmc   +1 more source

CTBPro: A Next‐Generation Cholera Toxin Subunit B‐Based Neuroanatomical Tracer With Superior Brightness, Stability, and Sensitivity for Enhanced Neural Circuit Mapping

Advanced Science, EarlyView.
CTBPro is a next‐generation cholera toxin B–based tracer engineered by fusing CTB to the ultra‐stable fluorescent protein mBaojin. Exhibiting markedly enhanced molar brightness, CTBPro enables high‐fidelity neuronal labeling across multiple administration routes.
Xinghua Quan, Yude Lou, Huiqi Xie, Yifei Wang, Yanzhe Zhang, Yiran Ge, Linhe Yang, Xiaoxuan Zhang, Qingmiao Zhou, Huaizong Shen, Longxing Cao, Xin Jin, Jie‐Min Jia   +12 more
wiley   +1 more source

Precepting in health professions education in Minnesota: motivators and inhibitors. [PDF]

BMC Med Educ
Fritsma T, Woldegerima S, Rosenberg ME, Weirick ME, Henning-Smith C, MacDougall H, Olson APJ.   +6 more
europepmc   +1 more source

Large‐Scale Genomics Reveals Three‐Source Ancestry and Layered Adaptation to High Altitude in Tibetan Chickens

Advanced Science, EarlyView.
Whole‐genome analysis of 1,054 chickens reveals three ancestral sources (NWC, SYA, and SHF) with distinct temporal entry patterns into the Tibetan Plateau. Route‐specific selection scans, calibrated against a demographic null, suggest complementary functional enrichments—vascular homeostasis (NWC), calcium signaling and cardiac adaptation (SYA), and ...
Zongyi Zhao, Ruixue Nie, Hailu Fan, Tenzin Ngodroup, Li Zhu, Hongbin Pan, Bo Zhang, Hao Zhang   +7 more
wiley   +1 more source

The living will system in mainland China: legislative status quo, dilemmas and prospects. [PDF]

Front Public Health
Tian L.
europepmc   +1 more source

MEOX1 Coordinates Autocrine‐Paracrine Programs via SPHK1/S1P to Promote Lymph Node Metastasis in Ovarian Cancer

Advanced Science, EarlyView.
In ovarian cancer, MEOX1 activates the SPHK1/S1P pathway to promote both tumor progression and tumor–stroma crosstalk. MEOX1‐dependent signaling drives CAF activation, enhances VEGF‐C expression, and stimulates lymphangiogenesis, ultimately facilitating lymph node metastasis.
Jiajia Li, Xiuling Zhi, Qianhan Lin, Yating Sun, Yihua Sun, Zulimire Abudousalamu, Mengyang Xue, Chang Zheng, Xiaotian Li, Liangqing Yao, Mo Chen   +10 more
wiley   +1 more source

Beyond the 72 h window: operationalizing safe abortion as essential care for sexual violence survivors in humanitarian settings. [PDF]

Front Reprod Health
Mambo SB, Mweze BA, Lubaliro I, Byamungu M, Lobo NJ, Agossou BU, Bizimana GN.   +6 more
europepmc   +1 more source

Tumor‐Intrinsic ARHGEF3 Enhances Antitumor Immunity by Promoting T‐Cell Infiltration and Limiting Myeloid Cell‐Mediated Immunosuppression

Advanced Science, EarlyView.
ARHGEF3 is broadly downregulated across human cancers and correlates with patient prognosis. Tumor‐intrinsic ARHGEF3 activates the RHOA–ROCK–PTEN cascade to inhibit AKT signaling, thereby promoting chemokine‐driven T‐cell infiltration and relieving lipid‐mediated myeloid immunosuppression.
Yue Li, Lan Wang, Zihao Zhang, Chunmei Qian, Ning Li, Wei Huang, Qian Ba, Xiaojian Liu, Mayu Sun   +8 more
wiley   +1 more source

Transition to adolescence in neurodevelopmental disorders: challenges and clinical perspectives. [PDF]

J Pediatr (Rio J)
Silva EJCD, Eisenstein E.
europepmc   +1 more source

From Asylum to Autonomy: Coercive Control, Consent Under Duress, and the Invisible Statute of Limitation

The historic practice of committing women to asylums under patriarchal authority persists today in subtler legal and therapeutic forms. Victims of coercive control are frequently redirected into mediation, counselling, or psychiatric treatment where their distress is reframed as dysfunction. Drawing on de La Rosière’s Ambience Violence Indicator (AVI),
openaire   +1 more source