Results 201 to 210 of about 2,091 (258)

Is Mental Capacity Law Law? [PDF]

Oxf J Leg Stud
Coggon J.
europepmc   +1 more source

ZER1 Restrains Pressure Overload‐Induced Cardiac Remodeling by Targeting DVL2 for Gly/N‐Degron‐Dependent Degradation

Advanced Science, EarlyView.
Pressure overload suppresses cardiomyocyte ZER1, weakening CRL2Zer1‐mediated DVL2 degradation and allowing DVL2 accumulation. Elevated DVL2 activates CaMKII‐HDAC4‐MEF2C signaling, drives fetal gene reactivation, and promotes pathological remodeling.
Mingchao Jiang, Zhehao Lin, Lu Chen, Ying Ni, Jun Zhou, Wenjuan Zhang, Huilin Wang, Peifeng Ying, Xiu Lu, Kai Wang, Qingran Kong, Naxin Xu, Dingsheng Zhao, Jianwei Li, Guohui Zhong, Xingchen Meng, Sarkawt Hamad, Junmeng Zheng, Yuan Fu, Rongjiang Qin, Xuran Chu, Shangxuan Li, Youyou Li, Yili Wu, Yi Wang, Weihong Song, Yingxian Li, Shukuan Ling   +27 more
wiley   +1 more source

The economics of digitally integrated wellness services in heritage regions. [PDF]

Front Digit Health
Alimova S, Vakhabova D, Akramov V.
europepmc   +1 more source

ROS‐Targeted Nanomotor Therapy in OA: Cartilage Protection and Pain Relief

Advanced Science, EarlyView.
ROS‐responsive NM@MET nanomotors utilize elevated ROS in osteoarthritic joints to promote deep penetration into cartilage and synovium and enable sustained metformin release. By scavenging ROS, regulating NRF2/KEAP1 signaling, protecting chondrocytes, suppressing synovial inflammation, and attenuating nociceptive signaling, NM@MET alleviates pain and ...
Meng Zheng, Changyu Liu, Qin Xia, Arndt F. Schilling, Jiawei Jiang, Renpeng Peng, Zixing Shu, Tian Ma, Danni Luo, Yaoyu Zhang, Yibo Fan, Xuyuan Zhang, Song Li, Kai Wang, Wentao Ke, Yuan Xiong, Yuanli Zhu, Fangzhi Mou, Jun Xiao, Hao Zhu   +19 more
wiley   +1 more source

Elites' perceptions of women's representation in the Omani media. [PDF]

Front Sociol
Al-Wahaibi S.
europepmc   +1 more source

Re-imagining approaches for mental health and substance use health workforce regulation in Canada: Making room for dynamic tensions. [PDF]

PLOS Ment Health
Slipp M, Myles S, Atanackovic J, Garner G, Bartram M, Bourgeault IL, Leslie K.   +6 more
europepmc   +1 more source

Individual, interpersonal, organizational, and community contexts: factors associated with alcohol consumption among Brazilian adolescents. [PDF]

BMC Pediatr
Coelho LM, Abreu MNS, Ramirez EGL, Cury LS, da Silva AG.   +4 more
europepmc   +1 more source

Pubertal Suppression for Transgender Youth: A Right to an Open Future Approach in Support of a Youth-Empowered Legal Framework. [PDF]

J Bioeth Inq
Lee R.
europepmc   +1 more source

Interventions by Rehabilitation Nurse Specialists in the Training of Informal Carers of Older People at Home with Chronic Diseases: A Scoping Review. [PDF]

Int J Environ Res Public Health
Bento AR, Duque AR, Gonçalves N, Vaz P, Calção S, Benedito V, Ferreira R, Fonseca C, Silva C.   +8 more
europepmc   +1 more source

The Greenland Model and Its Relevance to an Autonomy Statute for the Sahara Region

, 2013
openaire   +1 more source