Complementarity of Long‐Reads and Optical Mapping in Parkinson's Disease for Structural Variants
ABSTRACT Objective Long‐read sequencing and optical genome mapping technologies have the ability to detect large and complex structural variants. This has led to the discovery of novel pathogenic variants in neurodegenerative movement disorders. Thus, we aimed to systematically compare the SV detection capabilities of OGM and ONT in Parkinson's disease.
André Fienemann +17 more
wiley +1 more source
Clinical Characteristics of Adults at Risk of Medicaid Disenrollment Due to HR 1 Work Requirements. [PDF]
Chetty AK, Ross JS, Chen AS.
europepmc +1 more source
Validity of a Wearable Digital Insole for Assessing Gait ON and OFF in Parkinson's Disease
ABSTRACT Objective Gait impairment is a distinctive symptom of Parkinson's disease that negatively impact mobility. We assessed the validity of wearable digital insoles against a validated reference gait analysis system for measuring select gait characteristics in patients with Parkinson's disease. Methods A comparative analysis between digital insoles
Deborah A. Hall +16 more
wiley +1 more source
Image Sensor-Supported Multimodal Attention Modeling for Educational Intelligence. [PDF]
Chen Y +6 more
europepmc +1 more source
The Statute of Limitations for Profession Malpractice in Alaska after Lee Houston & Associates, Ltd. v. Racine [PDF]
Altes, Scott Lawrence
core +1 more source
Vestibular Patient Journey: Insights From Vestibular Disorders Association (VeDA) Registry
ABSTRACT Objective Vestibular symptoms impose a high burden of disability. Understanding real‐world diagnostic and treatment pathways can identify care gaps and guide interventions. We aimed to characterize symptom profiles, diagnostic trends, provider involvement, and treatment patterns in vestibular disorders.
Ali Rafati +10 more
wiley +1 more source
Drugs anticipated to be selected for Medicare price negotiation in 2026 for implementation in 2028. [PDF]
Cousin EM +4 more
europepmc +1 more source
ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen +7 more
wiley +1 more source
Obstetric-Related Emergency Medical Treatment and Labor Act Violations and No Health Exception Bans.
Woskie LR, Brower N, Shaffer J, Ladin K.
europepmc +1 more source
Artificial intelligence translation in healthcare: an urgent call for evidence-informed policy frameworks. [PDF]
Anyaegbuna C +8 more
europepmc +1 more source

