Results 61 to 70 of about 321,647 (305)

Trafik Sigortasında Dava Açılmadan Önce Sigortacı Tarafından Zarar Görene Yapılan Ödemenin Zamanaşımını Kesip Kesmediği Meselesi

Anadolu Üniversitesi Hukuk Fakültesi Dergisi
Karayolları Trafik Kanunu’nun 97’nci maddesine göre zarar görenin, karayolları motorlu araçlar zorunlu mali sorumluluk sigortasında öngörülen sınırlar içinde sigortacıya karşı dava yoluna gitmeden önce ilgili sigortacıya yazılı başvuruda bulunması ...
Abdülhamid Oğuzhan Hacıömeroğlu
doaj   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Perspectives juridiques sur le passé colonial belge, entre déni et justice

Criminocorpus
The Belgian colonial past is re-emerging in public debate, from parliamentary circles to courtrooms, not to mention places of action and militancy within civil society.
Marie-Sophie de Clippele
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Problematika Pembuktian dan Daluarsa dalam Penuntasan Pelanggaran HAM 1965–1966

Jurnal Nuansa Akademik
The 1965–1966 tragedy was one of the most systematic gross human rights violations in Indonesian history, involving mass killings, arbitrary detentions, torture, and enforced disappearances.
Wahyu Sinaga, Diki Zukriadi
doaj   +1 more source

Blind Dates: When Should the Statute of Limitations Begin to Run on a Method-of-Execution Challenge? [PDF]

, 2011
This Article is the first to take a comprehensive look at the issue of statute-of-limitations accrual in method-of-execution cases. In other words, when does the clock start ticking on a death row inmate\u27s right to challenge the way in which the state
Alper, Ty
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Illegal Crossing of the State Border in Light of Polish Criminal Law

Kyiv-Mohyla Law and Politics Journal, 2016
The subject of this paper is the illegal crossing of the Polish border. The paper focuses on criminal law issues. To explain the element “in violation of the relevant regulations,” being one of the elements of the criminal offences regarding the illegal ...
Katarzyna Banasik
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source