Results 61 to 70 of about 322,946 (297)

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Choice of Law as Extraterritoriality [PDF]

open access: yes, 2020
This contribution to Resolving Conflicts on the Law: Essays in Honour of Lea Brilmayer (published under the title Choice of Law as Geographic Scope Limitation) argues that the choice-of-law question commonly addressed by state and foreign courts is ...
Vázquez, Carlos Manuel
core   +1 more source

Sudan, Resolution 1593, and International Criminal Justice [PDF]

open access: yes, 2006
The UN Security Council has recently referred the situation in Darfur, Sudan, to the International Criminal Court. This has been hailed as a breakthrough in international criminal justice.
Cryer, Robert
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Trafik Sigortasında Dava Açılmadan Önce Sigortacı Tarafından Zarar Görene Yapılan Ödemenin Zamanaşımını Kesip Kesmediği Meselesi

open access: yesAnadolu Üniversitesi Hukuk Fakültesi Dergisi
Karayolları Trafik Kanunu’nun 97’nci maddesine göre zarar görenin, karayolları motorlu araçlar zorunlu mali sorumluluk sigortasında öngörülen sınırlar içinde sigortacıya karşı dava yoluna gitmeden önce ilgili sigortacıya yazılı başvuruda bulunması ...
Abdülhamid Oğuzhan Hacıömeroğlu
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Trade Regulation: Section 5(b) of the Clayton Act Given an Independent Role [PDF]

open access: yes, 1967
Section 5(b) of the Clayton Act, which provides for suspension of the applicable statute of limitations during the pendency of Government antitrust litigation, has traditionally been limited to those cases where a Government-obtained judgment was ...

core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Perspectives juridiques sur le passé colonial belge, entre déni et justice

open access: yesCriminocorpus
The Belgian colonial past is re-emerging in public debate, from parliamentary circles to courtrooms, not to mention places of action and militancy within civil society.
Marie-Sophie de Clippele
doaj   +1 more source

In Pursuit of Justice: Debating the Statute of Limitations for Nazi War Crimes in Britain and West Germany during the 1960s. [PDF]

open access: yes, 2015
Up until 1979, the ability of West German courts to prosecute Nazi war criminals was hampered by a Statute of Limitations for acts of manslaughter and murder.
Sharples, Caroline
core   +1 more source

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