Results 191 to 200 of about 12,972,158 (310)

A Retrospective Within-Subjects Analysis of Vancomycin Bayesian Modeling With Pre-steady-State vs Steady-State Concentrations. [PDF]

J Pharm Technol
Covington EW, Chae JL, Gunter SG.
europepmc   +1 more source

New electronic state documents list - November 2023

The monthly New South Carolina State Documents publication by the State Library provides a list of state documents published by state agencies that have been cataloged and added to the South Carolina State Documents Depository.
South Carolina State Library
core  

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Clinical and laboratory characteristics of adolescents and young adults with sickle cell disease at steady state in Uganda. [PDF]

PLOS Glob Public Health
Ssekandi AM, Namazzi R, Muwonge H, Kalyesubula R, Munabi IG, Sekaggya-Wiltshere C, Namaganda A, Kimuli I, Akugizibwe R, Kasujja H, Mukunya D, Ndeezi G, Kiguli S.   +12 more
europepmc   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Steady-state mobilization with on-demand plerixafor after CD38 antibody-based induction in multiple myeloma patients. [PDF]

Transfusion
Röhnert MA, Seifert A, Trautmann-Grill K, Röllig C, Zimmer K, Egger-Heidrich K, Bill M, Heberling L, Schulze F, Blechschmidt M, von Bonin M, Bornhäuser M, Hölig K, Teipel R.   +13 more
europepmc   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Activating plasmonic catalysis through light-mediated steady-state spin modulation. [PDF]

Nat Commun
Hu X, Liu J, Zhu Z, Liu S, Wang L, Cheng J, Huang X, Li C, Feng K, Zhou Y, Xu Y, Feng Q, Zhang B, Chen X, Zhang L, Zhang Q, Wu B, Yin J, An X, Zhang XH, He L.   +20 more
europepmc   +1 more source

Steady-State [PDF]

, 2020
openaire   +1 more source

New electronic state documents list -February 2024

The monthly New South Carolina State Documents publication by the State Library provides a list of state documents published by state agencies that have been cataloged and added to the South Carolina State Documents Depository.
South Carolina State Library
core