Results 91 to 100 of about 17,957,190 (298)

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Steady-state sensitivity analysis for inhibitor doses.

open access: yes, 2019
Note that inhibitor treatments are plotted as multiples of the standard dose (6.12×107 inhib. cm−3). In Cases A and B the number of bound bacteria, BB, is a monotone decreasing function of the inhibitor dose, , while the number of free bacteria, BF ...
Sara Jabbari (665782)   +4 more
core   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Steady-state kinetics of BVMOAFL838 with octanone.

open access: yes, 2016
Steady-state kinetics of BVMOAFL838 with octanone.
Martha Sophia Smit (3144627)   +3 more
core   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Variable Tap-Length Algorithm with Mixed Parameter

open access: yesApplied Sciences, 2018
Convergence speed and steady-state performance are important factors to estimate the variable tap-length algorithm. The step-size of tap-length (ST) and the error width considerably impact the performance of the fractional variable tap-length algorithm ...
Yufei Han, Mingjiang Wang, Yun Lu
doaj   +1 more source

Fundamentals of equilibrium and steady-state thermodynamics /

open access: yes, 2000
This book summarizes the salient features of both equilibrium and steady-state thermodynamic theory under a uniform postulatory viewpoint. The emphasis is upon the formal aspects and logical structure of thermodynamic theory, allowing it to emerge as a ...
Tschoegl, Nicholas W.
core  

Steady-state expression levels of mutant β clamp proteins.

open access: yes, 2016
Steady-state expression levels of mutant β clamp proteins.
Michael T. Nanfara (3186057)   +3 more
core   +1 more source

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