Results 181 to 190 of about 698,757 (298)

Dynamic Transitions for Fast Joint Acquisition and Reconstruction of CEST- Rex$$ {R}_{ex} $$ and T1$$ {T}_1 $$. [PDF]

Magn Reson Med
Huemer M, Stilianu C, Scholand N, Mackner D, Uecker M, Zaiss M, Stollberger R.   +6 more
europepmc   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

A novel hyperbolic tangent-based PID controller tuned by the artificial lemming algorithm for nonlinear steam condenser pressure control. [PDF]

Sci Rep
Ekinci S, Izci D, Jabari M, Çelik E, Bajaj M, Vishnuram P, Rubanenko O.   +6 more
europepmc   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

The variable relationship between initial connectance and community stability (community persistence at steady state; mean standard deviation based on 2020 replicates) in general MEST communities.

Lin Wang (11986), Ting Wang (16292), Xiao-Wei Zhang (205690), Xiao-Fen Lin (21688798), Jia Li (160557), Jin-Bao Liao (21688801), Rui-Wu Wang (257560)   +6 more
openalex   +1 more source

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

FEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi, Shunsuke Morioka, Keiko Morisawa, Kazutsugu Matsukawa, Shingo Ashida, Takeshi Suzuki, Shuji Sakamoto   +6 more
wiley   +1 more source

Verification and Validation of an Autotuning Proportional-Integral-Derivative Controller for Spatially Confined Magnetic Particle Hyperthermia. [PDF]

J Med Device
Pawar S, Carlton H, Lad YS, Werhane L, Abu-Ayyad M, Korangath P, Ivkov R, Attaluri A.   +7 more
europepmc   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

FEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Photothermal Evaluation of Aqueous Magnetite Nanodispersions: Accuracy, Precision, and Limitations. [PDF]

Molecules
Khabibullin VR, Ratova DV, Andreeva KO, Vershinina YS, Mikheev IV, Shtykov SN, Proskurnin MA.   +6 more
europepmc   +1 more source