Results 161 to 170 of about 418,709 (308)

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

A Novel Algebraic Saturation-Based PID Controller Optimized by Animated Oat Algorithm for Ultra-Fast Dynamic Response of Automatic Voltage Regulation. [PDF]

Biomimetics (Basel)
Türksoy Ö.
europepmc   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Highly Trained Female Runners Show Greater Durability and Physiological Resilience Than Performance-Matched Male Counterparts. [PDF]

Scand J Med Sci Sports
Jaén-Carrillo D, Bruce CD, Lawley JS, Zanini M.   +3 more
europepmc   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Simplified Analysis of Steady-State Performance of a Voltage Controlled Induction Motor Drive

, 1988
Utilizing a circuit model [1, 2] of an induction motor, a simplified analysis of steady state performance of a voltage controlled induction motor (VCIM) drive is described in this paper.
Prabhakaran, N, Padiyar, KR
core  

Tribological Performance of Femtosecond Laser-Fabricated Biomimetic Sinusoidal-Circular Composite Textures on 40Cr Steel Under Oil Lubrication. [PDF]

Materials (Basel)
Chen Y, Xu P, Zhao L, Yu Y, Wu Z.
europepmc   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Leakage analysis of gasketed flange joints under combined internap pressure and thermal loading

, 2011
Leakage in Gasketed Flanged Joints (GFJs) have always been a great problem for the process industry. The sealing performance of a GFJ depends on its installation and applied loading conditions.
Khan, Kamran Ahmed, Abid, Muhammad, Nash, David, Chatta, Javed Ahmad   +3 more
core  

Significance of oscillatory TiO₂-water nanofluid and heat transfer performance over vertical magnetized flat plate using artificial neural network. [PDF]

Discov Nano
Ullah Z, Alam MM, Alamirew WD, Said MA, Alsulami MD, Mahrous YM, Gnaba HA, Hussain F.   +7 more
europepmc   +1 more source