Results 41 to 50 of about 37,370,397 (253)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Steady-state kinetics analysis of recombinant TbAdoMetSyn.
, 2018 Steady-state kinetics analysis of recombinant TbAdoMetSyn.
Christopher Leija (3334554) +4 more
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Rapid magnetic resonance tissue relaxometry in the steady state [PDF]
, 2015 Longitudinal (T1) and transverse (T2) relaxation are the most fundamental physical processes governing the signal intensity and the soft tissue contrast in magnetic resonance imaging (MRI).
Heule, Rahel Maria +1 more
core +1 more source
SSCAR-Steady State Cycle AnalyseR
, 2017 This report describes the Steady-State Cycle AnalyseR (SCCAR), a solution engine that enables the steady state evaluation of thermodynamical cycles. SCCAR can be used to parametrically define thermodynamic cycles using a library of predefined building ...
Jahn, Ingo
core +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
, 2019 Four stacked bars are plotted for each case: the first bar shows the number of free and bound susceptible bacteria, and , at steady-state in the untreated scenario; the second bar shows the number of free and bound resistant bacteria, and , at steady ...
Sara Jabbari (665782) +4 more
core +1 more source
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Steady-state sensitivity analysis for inhibitor doses.
, 2019 Note that inhibitor treatments are plotted as multiples of the standard dose (6.12×107 inhib. cm−3). In Cases A and B the number of bound bacteria, BB, is a monotone decreasing function of the inhibitor dose, , while the number of free bacteria, BF ...
Sara Jabbari (665782) +4 more
core +1 more source
Steady-state simulation scenarios, and computation methods for ASA.
, 2023 (a) Different scenarios requiring computation of the model steady state. Top: The pre-equilibration case, where the system is at steady state at the beginning of the experiment. This means that by t = t0 the system has reached its steady state (x*) under
Paul Stapor (8370540) +8 more
core +1 more source