Results 81 to 90 of about 2,610,566 (293)

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

open access: yesFEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li   +6 more
wiley   +1 more source

PERFECTION OF CONSTRUCTION OF THE COOLING DEVICES OF THE COOLING LINES OF THE BAR REINFORCING ROLLED PRODUCTS OF RUP "BMZ"

open access: yesЛитьë и металлургия, 2006
The peculiarities of construction of thermomechanical hardening of rolled metal of operating line of the m ill 3 20 cooling are considered, their merits and demerits are analyzed.
S. M. Zhuchkov   +7 more
doaj  

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

open access: yesFEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru   +6 more
wiley   +1 more source

Gas metal arc welding of modified X2CrNi12 ferritic stainless steel [PDF]

open access: yes, 2007
X2CrNi12 ferritic stainless steel is a low cost stainless steel grade exhibiting good corrosion and abrasion resistance. Typical applications for this steel are bus frames and chassis, railway wagons for coal and iron ore, mining and mineral processing ...
Deleu, E.   +3 more
core   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

open access: yesFEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik   +6 more
wiley   +1 more source

FETTLING OF UNITS OF THE METAL BOTTOM BLOWING OF BLAST STEEL-FURNACE

open access: yesЛитьë и металлургия, 2007
The research work on unification of the units fettling of the metal bottom blowing with inert gas is carried out on the arc steel furnaces No 1, 2, 3.
M. A. Murikov   +4 more
doaj  

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

open access: yesFEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar   +4 more
wiley   +1 more source

ASSIMILATION OF THE ROUND WITH DIAMETER 160 MM IN CONDITIONS OF MILL 850 AT RUP “BMZ”

open access: yesЛитьë и металлургия, 2007
The developed temperature regimes of metal heating, energy-power and temperature parameters of rolling provided receiving of geometrical sizes, mechanical and metallographic investigations of hot-rolled round rolled metal with diameter 160 mm.
M. A. Murikov   +4 more
doaj  

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

open access: yesAging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Fluid and Neuroimaging Biomarkers in Microgliopathy Colony‐Stimulating Factor‐1 Receptor‐Related Disorders

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aims to identify both fluid and neuroimaging biomarkers for CSF1R‐RD that can inform the optimal timing of treatment administration to maximize therapeutic benefit, while also providing sensitive quantitative measurements to monitor disease progression.
Tomasz Chmiela   +13 more
wiley   +1 more source

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