Results 41 to 50 of about 308,481 (314)
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
A STUDY OF REINFORCED CONCRETE COLUMN STRUCTURE TO COMPARE OF STEEL COLUMN STRUCTURE (CASE STUDY ON INDONESIA EDUCATION MUSEUM BUILDING YOGYAKARTA STATE UNIVERSITY) [PDF]
, 2011 Indonesia education museum building which consists of two floors has a unique architectural style and in the earthquake zone 3, its design is using a system of intermediate moment frame bearers (SRPMM) to carry the gravity and seismic loads. The frame
Yudha Febry Anggriawan, Yudha Febry Anggriawan
core
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Experimental studies on the effect of nano silica modified novel concrete CFST columns
Materials Research Express, 2023 Under axial compression, the present article analyses and compares the behaviour of Plain Concrete filled and Nano Silica modified concrete filled with light gauge steel rectangular columns. In 18 work samples, plain and nano silica-modified concrete was
P Vasanthi +3 more
doaj +1 more source
Investigation of Circular Hollow Concrete Columns Reinforced with GFRP Bars and Spirals
Buildings, 2023 Glass fiber-reinforced polymer (GFRP) reinforcements are useful alternatives to traditional steel bars in concrete structures, particularly in vertical structural elements such as columns, as they are less prone to corrosion, and impart increasing ...
Afaq Ahmad +4 more
doaj +1 more source
Improved behaviour of concrete-filled-stee-tube columns with external confinement [PDF]
, 2011 In high-strength concrete columns, because of the heavy demand of confining steel to restore the column ductility, it is more efficient to provide the confinement in the form of steel tube to form concrete-filled-steel-tube (CFST) column.
Ho, JCM
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Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
Behaviour of concrete filled stainless steel elliptical hollow sections [PDF]
, 2008 This paper presents the behaviour and design of axially loaded concrete filled stainless steel elliptical hollow sections. The experimental investigation was conducted using normal and high strength concrete of 30 and 100 MPa. The current study is based
Burdett, M., Gardner, L., Lam, D.
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Molecular Oncology, EarlyView.To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source
Buildings, 2023 In this paper, a finite element model of concrete-filled steel tubular (CFST) columns under compression and lateral impact is developed and validated against previous experiments.
Man Xu +3 more
doaj +1 more source