Results 41 to 50 of about 957,059 (286)

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Analysis of mechanical properties in self‐compacting concrete enhanced with steel fibres

Micro & Nano Letters
This study explores the effect of incorporating steel fibres and fly ash into self‐compacting concrete (SCC) in various combinations on its mechanical properties.
Mukilan Karuppasamy, Baranitharan Balakrishnan, Karthik Chandran, Mehdi Gheisari, Payam Porkar Rezaeiye, Boris Andrievsky   +5 more
doaj   +1 more source

Investigating the behaviour of hybrid fibre-reinforced reactive powder concrete beams after exposure to elevated temperatures

Journal of Materials Research and Technology, 2020
This study investigated the structural behaviour of reinforced reactive powder concrete (RPC) beams under service load and fire exposure. The beams were composed of hybrid fibres (50% polypropylene fibres and 50% steel fibres) at different volume ...
Al-Attar Alyaa A., Abdulrahman Mazin B., Hamada Hussein M., Tayeh Bassam A.   +3 more
doaj   +1 more source

Impact of Steel Fibre Reinforcement on the Strength of Steel Anchors

IOP Conference Series: Materials Science and Engineering, 2020
Abstract The paper presents methods of fastening using expansion fasteners and concrete screws anchored in conventional concrete and in fibre reinforced concrete. It addresses ways to determine the strength of such joints based on the EOTA (European Organisation for Technical Assessment) Guidelines and US Recommendations.
Daniel Dudek, Kazimierz Konieczny
openaire   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Modern concrete pipes: a review of reinforcement and new technologies

Studia Geotechnica et Mechanica, 2021
The paper discusses existing reinforcement, future reinforcement and new technologies for concrete pipes used in the sewage systems. Concrete pipes currently in use and under investigation are reviewed.
Abel Tomasz, Pelczar Natalia
doaj   +1 more source

Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach, Sandra Donkervoort, Carola Hedberg‐Oldfors, Giovanni Baranello, Dimah Saade, Precilla D'Souza, Ruchee Patel, Eva Michael, A. Reghan Foley, Diana Bharucha‐Goebel, S. Jin Haugland, Meghan McAnally, Omer Abdul Hamid, Katherine Chao, Ellen F. Macnamara, Alan H. Beggs, Anna Sarkozy, Juliane Mueller, Steven A. Moore, Richard S. Finkel, Cynthia J. Tifft, Francesco Muntoni, Anders Oldfors, Carsten G. Bönnemann   +23 more
wiley   +1 more source

Flexural behaviour and punching shear of selfcompacting concrete ribbed slab reinforced with steel fibres

MATEC Web of Conferences, 2017
This paper investigates the effects of steel fibres as a replacement to the conventional reinforcement under flexural behaviour and punching shear in self-compacting (SCC) ribbed slab reinforced with steel fibres.
Ahmad Hazrina, Mohd Hashim Mohd Hisbany, Abu Bakar Afidah, Hamzah Siti Hawa   +3 more
doaj   +1 more source