Results 31 to 40 of about 47,365 (264)
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Controls of root-system overlap on hillslope stability
Communications Earth & EnvironmentMore frequent extreme rainfall has heightened the need to understand vegetation’s influence on slope stability in steep terrain. Among vegetation-related factors, root-system overlap, the intersection of neighboring root networks, remains understudied ...
Rozaqqa Noviandi +4 more
doaj +1 more source
Buildings, 2022 Integrating the concepts of frictional energy dissipation and low-damage mechanism, this paper proposes a built-in continuous-column (BCC) steel moment frame structure with low-damage cover plate slip-friction connections (CPSFCs) at the column bases ...
Chengyu Li, Runing Bai, Bo He, Aizhu Zhu
doaj +1 more source
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
工程科学与技术, 2023 A prefabricated lightweight steel composite frames–perlite insulation reinforced with steel wire mesh composite wall (PSW) structure suitable for low-rise buildings in villages was proposed.
Wanlin CAO +3 more
doaj
Experiment and Numerical Simulation of Wooden Door Frame
Advances in Materials Science and Engineering, 2021 To prevent the wooden door frame of traditional rural houses from being stuck due to diamond deformation under earthquake and improve the seismic capacity of rural houses, an innovative method of reinforcing the angular displacement of the wooden door ...
Eryu Zhu, Bin Wang, Dongqi Wei, Li Zhu
doaj +1 more source
Applied Sciences, 2023 In order to improve the progressive collapse resistance of an RC frame structure with an L-shaped plane under local component failure, X-tension reinforcement and steel trusses are applied to the progressive collapse resistance design. In this paper, the
Yifei Dai, Lei Qin
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NUMERICAL MODEL FOR ANALYSIS OF STEEL FRAME STRUCTURES WITH INCLUDED GEOMETRIC IMPERFECTIONS [PDF]
e-Zbornik. Elektronički Zbornik Radova Građevinskog Fakulteta, 2020 Numerical model based on finite element method for analysis of steel frame structures is presented. Model is implemented in computer program [9] and implies application of 1D (beam) finite element.
Radoslav Markić
doaj +1 more source
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti +5 more
wiley +1 more source