Results 41 to 50 of about 232,180 (310)
Emerging steel frames with Fe-SMA U-shaped dampers for enhancing seismic resilience
Journal of Infrastructure Preservation and Resilience, 2023 Post-earthquake financial loss of structures induced by residual inter-story deformation (RID) has been recently noticed and various strategies have been proposed. A newly-emerged energy-dissipation material, namely, iron-based shape-memory-alloy (Fe-SMA)
Zhe-Xi Zhang +4 more
doaj +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
BuildingsThe construction industry presents a significant environmental challenge due to its substantial environmental footprint, utilization of limited natural resources, and contribution to pollution and climate change. Additionally, optimizing the weight, cost,
Mohammad Nader Negarestani +3 more
doaj +1 more source
Seismic vulnerability analysis of steel buildings in Bogotá, Colombia [PDF]
, 2012 A number of mid-height steel buildings have been erected recently in Bogotá. Their seismic risk might be high, given the new microzonation of Bogotá and the lack of previous studies; remarkably, the response reduction factors were commonly obtained from ...
López Almansa, Francisco +1 more
core
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
In-plane Behavior of Steel Frames with Various Infill Materials; A Parametric Finite Element Study [PDF]
پژوهشهای زیرساختهای عمرانیWith development of new technologies in recent years, traditional masonry infills have gradually been replaced by modern one like Concrete Sandwich Panels (CSP).
Hamzeh Omidvar +2 more
doaj +1 more source
Gas metal arc welding of modified X2CrNi12 ferritic stainless steel [PDF]
, 2007 X2CrNi12 ferritic stainless steel is a low cost stainless steel grade exhibiting good corrosion and abrasion resistance. Typical applications for this steel are bus frames and chassis, railway wagons for coal and iron ore, mining and mineral processing ...
Deleu, E. +3 more
core +1 more source
Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276
FEBS Open Bio, EarlyView.Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig +7 more
wiley +1 more source
Seismic efficiency of self-centering braced frame under near-field pulse-like ground motions [PDF]
مجله مدل سازی در مهندسی, 2018 This research investigates the efficiency of the self-centering steel braced frame equipped with replaceable yielding fuses and post-tensioning cables subjected to far-field records and near-field pulse-like ground motions.
نوید رهگذر +2 more
doaj +1 more source
Applied Sciences, 2023 In the construction of a twin-steel box-girder bridge, external cross-frames are temporarily used to increase torsional resistance. These members are regarded as secondary and are removed after a composite action in the bridge is achieved.
Janghwan Kim +2 more
doaj +1 more source