Results 41 to 50 of about 29,584 (314)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Design-Optimization of Conventional Steel Structures for Realization of the Sustainable Development Objectives Using Metaheuristic Algorithm

Buildings
The construction industry presents a significant environmental challenge due to its substantial environmental footprint, utilization of limited natural resources, and contribution to pollution and climate change. Additionally, optimizing the weight, cost,
Mohammad Nader Negarestani, Hooman Hajikandi, Bahador Fatehi-Nobarian, Javad Majrouhi Sardroud   +3 more
doaj   +1 more source

Emerging steel frames with Fe-SMA U-shaped dampers for enhancing seismic resilience

Journal of Infrastructure Preservation and Resilience, 2023
Post-earthquake financial loss of structures induced by residual inter-story deformation (RID) has been recently noticed and various strategies have been proposed. A newly-emerged energy-dissipation material, namely, iron-based shape-memory-alloy (Fe-SMA)
Zhe-Xi Zhang, Jie Zhang, Cheng Fang, Yuelin Zhang, Yuanmu Li   +4 more
doaj   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

Improving the Structural Reliability of Steel Frames Using Posttensioned Connections

Advances in Civil Engineering, 2019
In this paper, various moment-resisting steel frames (MRSFs) are subjected to 30 narrow-band motions scaled at different ground motion intensity levels in terms of spectral acceleration at first mode of vibration SaT1 in order to perform incremental ...
Edén Bojórquez, Arturo López-Barraza, Alfredo Reyes-Salazar, Sonia E. Ruiz, Jorge Ruiz-García, Antonio Formisano, Francisco López-Almansa, Julián Carrillo, Juan Bojórquez   +8 more
doaj   +1 more source

In-plane Behavior of Steel Frames with Various Infill Materials; A Parametric Finite Element Study [PDF]

پژوهش‌های زیرساخت‌های عمرانی
With development of new technologies in recent years, traditional masonry infills have gradually been replaced by modern one like Concrete Sandwich Panels (CSP).
Hamzeh Omidvar, Seyed Jafar Hashemi, Mahdi Yazdani   +2 more
doaj   +1 more source

High strength steel in seismic resistant building frames (HSS-SERF) [PDF]

, 2015
The aim of “HSS-SERF” project was to investigate and evaluate the seismic performance of dual-steel building frames, realized from two different steel grades: Mild Carbon Steel (MCS) and High Strength Steel (HSS).
Vulcu, C, D’Aniello, M, Tremeea, A., Stratan, A., Kuhlmann, H., Tenchini, A., Demonceau, J.-F., Braconi, A., Fulop, Ludovic, Kuhlmann, Ulrike, Fülöp, Ludovic; id_orcid, Comeliau, L., Rebelo, C., Kuhlmann, U, Salvatore, W., Cermelj, Blaz, Rebelo, Carlos, Demonceau, J. F, Kesti, J., Rasche, C., da Silva, Luis, Grecea, Daniel, Vulcu, C., D'aniello, Mario, Dubina, D, Comeliau, L, da Silva, L. S, Hoang, Van Long, Grecea, D, Stratan, A, da Silva, L.S., Caprili, S., Može, P, Rasche, C, Beg, D, Rebelo, C, Kesti, J, Beg, D., Tremeea, A, Ciutina, A, Hoang, L., PORTIOLI, FRANCESCO PAOLO ANTONIO, Fulop, L., Dubina, Dan, Ciutina, A., Vulcu, Cristian, Portioli, F, Dubina, D., Loan, A., Landolfo, Raffaele, Kesti, Jyrki, Ioan, A., Jaspart, Jean-Pierre, Landolfo, R, Cermelj, B, Salvatore, Walter, Kleiner, Adrian, Hoang, L, Fülöp, L, Kleiner, A, Portioli, F., Portioli, Francesco, Ferrini, M., Rasche, A., Ciutina, Adrian, Moze, P., Braconi, A, D’Aniello, M., Cermelj, B., Grecea, D., Beg, Darko, Ioan, A, Jaspart, Jean Pierre, Demonceau, Jean-François, Demonceau, Jean François, Comeliau, Ludivine, Jaspart, J-P., Kleiner, A., CAPRILI, SILVIA, Tenchini, A, Stratan, Aurel, Jaspart, J. P   +81 more
core   +1 more source

Baseline Regional Cholinergic Denervation Predicts Cognitive Trajectories in Moderate Parkinson Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cognitive decline is a disabling and variable feature of Parkinson disease (PD). While cholinergic system degeneration is linked to cognitive impairments in PD, most prior research reported cross‐sectional associations. We aimed to fill this gap by investigating whether baseline regional cerebral vesicular acetylcholine transporter ...
Taylor Brown, Giulia Carli, Prabesh Kanel, Stiven Roytman, Jaimie Barr, Nicolaas I. Bohnen, Roger L. Albin   +6 more
wiley   +1 more source

SPG4 and Dementia: Expanding the Clinical Spectrum

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza, Arun Meyyazhagan, Eliseo Picchi, Gustavo Ribas, Ingrid Faber, Ryosuke Miyamoto, Preethi Basavaraju, Paolo Eusebi, Haripriya Kuchi Bhotla, Mario Stasi, Fabrizio Gaudiello, Francesco Patti, Filippo Maria Santorelli, Marcondes Cavalcante França Jr, José Luiz Pedroso, Orlando Graziani Povoas Barsottini, Hélio Afonso Ghizoni Teive, Peter Henry St George‐Hyslop, Toshitaka Kawarai, Antonio Orlacchio   +19 more
wiley   +1 more source

Steel beam–column joint with discontinuous vertical reinforcing bars

Journal of Civil Engineering and Management, 2017
The authors have previously proposed steel beam–column connections for precast concrete frames. The steel–concrete composite frames combined the advantages of the fast assembly of steel and the low cost of concrete structures.
Ju-Yun Hu, Won-Kee Hong
doaj   +1 more source