Results 41 to 50 of about 3,796,291 (302)
Conceptual design of the steel industry in 2050 considering collaboration with local communities
This paper discusses the development of design methods for the steel industry that consider the geographical and social characteristics of industrial host communities for realizing a carbon–neutral society by 2050.
Akira Kishimoto +2 more
doaj +1 more source
GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain +11 more
wiley +1 more source
Steelmaking is essential to modern society but remains a major CO₂ emitter. To mitigate this, technologies like hydrogen-based steelmaking and alternative reducing agents are being explored.
Hiroki Umetsu +8 more
doaj +1 more source
The development of a high-efficiency aquaculture water pump using self-adhesive electrical steel
Traditional water pump use AC motor combines with gearbox to achieve high torque and low speed to protect fish form injury by blades, which will shorten the life of waterwheel.
Guan-Ming Chen +3 more
doaj +1 more source
The phenomena of melting and dendritic fragmentation are captured by using an in-situ device during the ultrasound-assisted solidification of a succinonitrile-acetone (SCN-ACE) alloy.
Yu Chen +3 more
doaj +1 more source
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen +8 more
wiley +1 more source
Dimethyl Fumarate, But Not Rituximab, Reduces Serum GFAP Levels and PIRMA in Relapsing–Remitting MS
ABSTRACT Objective Serum neurofilament light chain (sNfL) and glial fibrillary acidic protein (sGFAP) levels are believed to reflect mainly acute and chronic disease processes in multiple sclerosis (MS), respectively. In this study, we investigated whether dimethyl fumarate (DMF) and rituximab (RTX) differentially affect these biomarkers.
F. Shawket +14 more
wiley +1 more source
Mapping the global end-of-life vehicles to scale up circular economy
Summary: The vehicle industry is significantly improving our quality of life and promoting economic development. However, the large number of end-of-life vehicles (ELVs) deserves more attention since many valuable resources are embodied in them.
Xianlai Zeng +5 more
doaj +1 more source
Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD
ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin +11 more
wiley +1 more source
This study examines the microstructure and mechanical properties of 5356 aluminum alloy under low heat input conditions during arc additive manufacturing, focusing on the challenges posed by excessive heat input, which hinders specimen formation and ...
Xiaogang Zuo +4 more
doaj +1 more source

