Results 101 to 110 of about 47,553 (291)

No evidence of association between apolipoprotein E genotype and phenotypic severity in childhood onset proximal spinal muscular atrophy

, 1999
The survival motor neuron (SMN) gene is present in two copies on chromosome 5q13 and the evidence is now compelling that mutations in the telomeric copy (SMNt) of the gene underlie childhood onset proximal spinal muscular atrophy (SMA).
Dubowitz, Victor, Victor Dubowitz, Steers, Graham, Karen E Morrison, Morrison, Karen E.; id_orcid, Morrison, Karen E., Graham Steers   +6 more
core   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Comparative Analysis of Skeletal Muscle Satellite Cells from Hanwoo Steers and Cows for Optimizing Cell-Based Meat Production

Food Science of Animal Resources
This study aimed to compare the proliferation, differentiation rates, and related gene expression levels of skeletal muscle satellite cells (SMSCs) isolated from Hanwoo steers and cows to identify a suitable source for cell-based meat production.
Bosung Kim, Doyeon Kim, Yeongjun Choi, Jinsung Kim, Su-Hak Heo, Sungkwon Park   +5 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

The letter is addressed to Samuel D. Woodruff and is signed by Thomas Steers

Letter which is very stained, fragile and has holes in it. Text is partially illegible and faded. The letter is addressed to Samuel D. Woodruff and is signed by Thomas Steers. It is written in ink, but someone has added comments in pencil.
Steers, Thomas
core   +1 more source

Influence of mixing supplements (dry or liquid) with monensin or soluble protein on the feeding value of finishing diets for feedlot cattle

Journal of Applied Animal Research, 2018
The influence of supplement form (dry vs. liquid) on the feeding value of diets for feedlot cattle was evaluated. Treatments were: (1) dry supplement (DS); (2) liquid supplement (LS, all supplemental macro- and micro-minerals, salt, monensin and urea ...
J. Salinas-Chavira, Martin F. Montano-Gomez, Juan Diego Navarrete, Constantino Raymundo, N. G. Torrentera, R. A. Zinn   +5 more
doaj   +1 more source

The Affect of Animal Gender on Fed Cattle Producer Marketing Behavior [PDF]

Weekly grid market share by volume for slaughter steers is compared to slaughter heifers. Summary statistics indicate average grid market share for steers (42%) is 27% higher than slaughter heifers (33%).
Lange, Brent, Diersen, Matthew A., Li, Jing, Qasmi, Bashir A., Fausti, Scott W.   +4 more
core  

Effects of zeranol on bone growth and other carcass traits in steers and bulls

, 1985
The effects of zeranol were studied in 24 steers and 24 bulls starting at an average weight of 200 kg for a trial period of 183 days. Bulls grew faster than steers (P = 0.07) and zeranol-treated cattle showed higher average daily gain than controls (P ...
Price, M. A., Chaudhary, Z. I., Makarechian, M.   +2 more
core   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source